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The Role of Bioactive Compounds in Natural Products Extracted from Plants in Cancer Treatment and Their Mechanisms Related to Anticancer Effects

Cancer is one of the greatest causes of death worldwide. With the development of surgery, radiotherapy, and medical agents, the outcomes of cancer patients have greatly improved. However, the underlying mechanisms of cancer are not yet fully understood. Recently, natural products have been proven to...

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Detalles Bibliográficos
Autores principales: Yuan, Meng, Zhang, Guoqing, Bai, Weijun, Han, Xin, Li, Chan, Bian, Siman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863487/
https://www.ncbi.nlm.nih.gov/pubmed/35211240
http://dx.doi.org/10.1155/2022/1429869
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author Yuan, Meng
Zhang, Guoqing
Bai, Weijun
Han, Xin
Li, Chan
Bian, Siman
author_facet Yuan, Meng
Zhang, Guoqing
Bai, Weijun
Han, Xin
Li, Chan
Bian, Siman
author_sort Yuan, Meng
collection PubMed
description Cancer is one of the greatest causes of death worldwide. With the development of surgery, radiotherapy, and medical agents, the outcomes of cancer patients have greatly improved. However, the underlying mechanisms of cancer are not yet fully understood. Recently, natural products have been proven to be beneficial for various conditions and have played important roles in the development of novel therapies. A substantial amount of evidence indicates that bioactive compounds could improve the outcomes of cancer patients via various pathways, such as endoplasmic reticulum stress, epigenetic modification, and modulation of oxidative stress. Here, we review the current evidence of bioactive compounds in natural products for the treatment of cancer and summarize the underlying mechanisms in this pathological process.
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spelling pubmed-88634872022-02-23 The Role of Bioactive Compounds in Natural Products Extracted from Plants in Cancer Treatment and Their Mechanisms Related to Anticancer Effects Yuan, Meng Zhang, Guoqing Bai, Weijun Han, Xin Li, Chan Bian, Siman Oxid Med Cell Longev Review Article Cancer is one of the greatest causes of death worldwide. With the development of surgery, radiotherapy, and medical agents, the outcomes of cancer patients have greatly improved. However, the underlying mechanisms of cancer are not yet fully understood. Recently, natural products have been proven to be beneficial for various conditions and have played important roles in the development of novel therapies. A substantial amount of evidence indicates that bioactive compounds could improve the outcomes of cancer patients via various pathways, such as endoplasmic reticulum stress, epigenetic modification, and modulation of oxidative stress. Here, we review the current evidence of bioactive compounds in natural products for the treatment of cancer and summarize the underlying mechanisms in this pathological process. Hindawi 2022-02-15 /pmc/articles/PMC8863487/ /pubmed/35211240 http://dx.doi.org/10.1155/2022/1429869 Text en Copyright © 2022 Meng Yuan et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Yuan, Meng
Zhang, Guoqing
Bai, Weijun
Han, Xin
Li, Chan
Bian, Siman
The Role of Bioactive Compounds in Natural Products Extracted from Plants in Cancer Treatment and Their Mechanisms Related to Anticancer Effects
title The Role of Bioactive Compounds in Natural Products Extracted from Plants in Cancer Treatment and Their Mechanisms Related to Anticancer Effects
title_full The Role of Bioactive Compounds in Natural Products Extracted from Plants in Cancer Treatment and Their Mechanisms Related to Anticancer Effects
title_fullStr The Role of Bioactive Compounds in Natural Products Extracted from Plants in Cancer Treatment and Their Mechanisms Related to Anticancer Effects
title_full_unstemmed The Role of Bioactive Compounds in Natural Products Extracted from Plants in Cancer Treatment and Their Mechanisms Related to Anticancer Effects
title_short The Role of Bioactive Compounds in Natural Products Extracted from Plants in Cancer Treatment and Their Mechanisms Related to Anticancer Effects
title_sort role of bioactive compounds in natural products extracted from plants in cancer treatment and their mechanisms related to anticancer effects
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863487/
https://www.ncbi.nlm.nih.gov/pubmed/35211240
http://dx.doi.org/10.1155/2022/1429869
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