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The Role of Bioactive Compounds in Natural Products Extracted from Plants in Cancer Treatment and Their Mechanisms Related to Anticancer Effects
Cancer is one of the greatest causes of death worldwide. With the development of surgery, radiotherapy, and medical agents, the outcomes of cancer patients have greatly improved. However, the underlying mechanisms of cancer are not yet fully understood. Recently, natural products have been proven to...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863487/ https://www.ncbi.nlm.nih.gov/pubmed/35211240 http://dx.doi.org/10.1155/2022/1429869 |
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author | Yuan, Meng Zhang, Guoqing Bai, Weijun Han, Xin Li, Chan Bian, Siman |
author_facet | Yuan, Meng Zhang, Guoqing Bai, Weijun Han, Xin Li, Chan Bian, Siman |
author_sort | Yuan, Meng |
collection | PubMed |
description | Cancer is one of the greatest causes of death worldwide. With the development of surgery, radiotherapy, and medical agents, the outcomes of cancer patients have greatly improved. However, the underlying mechanisms of cancer are not yet fully understood. Recently, natural products have been proven to be beneficial for various conditions and have played important roles in the development of novel therapies. A substantial amount of evidence indicates that bioactive compounds could improve the outcomes of cancer patients via various pathways, such as endoplasmic reticulum stress, epigenetic modification, and modulation of oxidative stress. Here, we review the current evidence of bioactive compounds in natural products for the treatment of cancer and summarize the underlying mechanisms in this pathological process. |
format | Online Article Text |
id | pubmed-8863487 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-88634872022-02-23 The Role of Bioactive Compounds in Natural Products Extracted from Plants in Cancer Treatment and Their Mechanisms Related to Anticancer Effects Yuan, Meng Zhang, Guoqing Bai, Weijun Han, Xin Li, Chan Bian, Siman Oxid Med Cell Longev Review Article Cancer is one of the greatest causes of death worldwide. With the development of surgery, radiotherapy, and medical agents, the outcomes of cancer patients have greatly improved. However, the underlying mechanisms of cancer are not yet fully understood. Recently, natural products have been proven to be beneficial for various conditions and have played important roles in the development of novel therapies. A substantial amount of evidence indicates that bioactive compounds could improve the outcomes of cancer patients via various pathways, such as endoplasmic reticulum stress, epigenetic modification, and modulation of oxidative stress. Here, we review the current evidence of bioactive compounds in natural products for the treatment of cancer and summarize the underlying mechanisms in this pathological process. Hindawi 2022-02-15 /pmc/articles/PMC8863487/ /pubmed/35211240 http://dx.doi.org/10.1155/2022/1429869 Text en Copyright © 2022 Meng Yuan et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Yuan, Meng Zhang, Guoqing Bai, Weijun Han, Xin Li, Chan Bian, Siman The Role of Bioactive Compounds in Natural Products Extracted from Plants in Cancer Treatment and Their Mechanisms Related to Anticancer Effects |
title | The Role of Bioactive Compounds in Natural Products Extracted from Plants in Cancer Treatment and Their Mechanisms Related to Anticancer Effects |
title_full | The Role of Bioactive Compounds in Natural Products Extracted from Plants in Cancer Treatment and Their Mechanisms Related to Anticancer Effects |
title_fullStr | The Role of Bioactive Compounds in Natural Products Extracted from Plants in Cancer Treatment and Their Mechanisms Related to Anticancer Effects |
title_full_unstemmed | The Role of Bioactive Compounds in Natural Products Extracted from Plants in Cancer Treatment and Their Mechanisms Related to Anticancer Effects |
title_short | The Role of Bioactive Compounds in Natural Products Extracted from Plants in Cancer Treatment and Their Mechanisms Related to Anticancer Effects |
title_sort | role of bioactive compounds in natural products extracted from plants in cancer treatment and their mechanisms related to anticancer effects |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863487/ https://www.ncbi.nlm.nih.gov/pubmed/35211240 http://dx.doi.org/10.1155/2022/1429869 |
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