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Increased Levels of Interleukin-36 in Obesity and Type 2 Diabetes Fuel Adipose Tissue Inflammation by Inducing Its Own Expression and Release by Adipocytes and Macrophages

Interleukin (IL)-36 is a recently described cytokine with well-known functions in the regulation of multiple inflammatory diseases. Since no data exists on how this cytokine regulates adipose tissue (AT) homeostasis, we aimed to explore the function of a specific isoform, IL-36γ, an agonist, in huma...

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Detalles Bibliográficos
Autores principales: Frühbeck, Gema, Gómez-Ambrosi, Javier, Ramírez, Beatriz, Mentxaka, Amaia, Rodríguez, Amaia, Becerril, Sara, Reina, Gabriel, Valentí, Victor, Moncada, Rafael, Silva, Camilo, Catalán, Victoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863603/
https://www.ncbi.nlm.nih.gov/pubmed/35222417
http://dx.doi.org/10.3389/fimmu.2022.832185

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