Cargando…

Androgen Receptor Splicing Variant-7 in Breast Cancer: Clinical and Pathologic Correlations

Androgen receptor (AR) inhibitor therapy is a developing treatment for AR-positive breast cancer (BC) with ongoing clinical trials. AR splicing variant-7 (AR-V7) is a truncated variant of AR that leads to AR inhibitor therapy resistance in prostate cancer; recent studies have identified AR-V7 in BC...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ferguson, Donna C., Mata, Douglas A., Tay, Timothy KY., Traina, Tiffany A., Gucalp, Ayca, Chandarlapaty, Sarat, D’Alfonso, Timothy M., Brogi, Edi, Mullaney, Kerry, Ladanyi, Marc, Arcila, Maria E., Benayed, Ryma, Ross, Dara S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863633/ https://www.ncbi.nlm.nih.gov/pubmed/34593966 http://dx.doi.org/10.1038/s41379-021-00924-5

Ejemplares similares

Triple-Negative Breast Cancer: Adjuvant Therapeutic Options
por: Gucalp, Ayca, et al.
Publicado: (2011)

Palbociclib: an evidence-based review of its potential in the treatment of breast cancer
por: Cadoo, Karen A, et al.
Publicado: (2014)

Diagnosis of known sarcoma fusions and novel fusion partners by targeted RNA sequencing with identification of a recurrent ACTB-FOSB fusion in pseudomyogenic hemangioendothelioma
por: Zhu, Guo, et al.
Publicado: (2018)

Uterine mesenchymal tumors harboring ALK fusions and response to ALK-targeted therapy
por: Kyi, Chrisann, et al.
Publicado: (2021)

Ultrarapid EGFR Mutation Screening Followed by Comprehensive Next-Generation Sequencing: A Feasible, Informative Approach for Lung Carcinoma Cytology Specimens With a High Success Rate
por: Arcila, Maria E., et al.
Publicado: (2020)

Whole‐exome sequencing analysis of juvenile papillomatosis and coexisting breast carcinoma
por: D'Alfonso, Timothy M, et al.
Publicado: (2020)

Histone H3K36I mutation in a metastatic histiocytic tumor of the skull and response to sarcoma chemotherapy
por: Snuderl, Matija, et al.
Publicado: (2019)

Genetic and epigenetic landscape of IDH-wildtype glioblastomas with FGFR3-TACC3 fusions
por: Mata, Douglas A., et al.
Publicado: (2020)

Morphologic and Immunohistochemical Features of Carcinoma Involving Microglandular Adenosis of the Breast Following Neoadjuvant Chemotherapy
por: Grabenstetter, Anne, et al.
Publicado: (2021)

PDK1-SGK1 Signaling Sustains AKT-Independent mTORC1 Activation and Confers Resistance to PI3Kα Inhibition
por: Castel, Pau, et al.
Publicado: (2016)

Retained Mismatch Repair Protein Expression Occurs in Approximately 6% of Microsatellite Instability-High Cancers and is Associated with Missense Mutations in Mismatch Repair Genes.
por: Hechtman, Jaclyn F., et al.
Publicado: (2019)

TERT promoter hotspot mutations and gene amplification in metaplastic breast cancer
por: da Silva, Edaise M., et al.
Publicado: (2021)

Decoding the androgen receptor splice variants
por: Lu, Changxue, et al.
Publicado: (2013)

P2RY8-CRLF2 Fusion–Positive Acute Myeloid Leukemia With Myelodysplasia-Related Changes: Response to Novel Therapy
por: Aypar, Umut, et al.
Publicado: (2020)

Incidence of brain metastases in patients with early HER2-positive breast cancer receiving neoadjuvant chemotherapy with trastuzumab and pertuzumab
por: Ferraro, Emanuela, et al.
Publicado: (2022)

Identifying patients with NTRK fusion cancer
por: Solomon, J P, et al.
Publicado: (2019)

Incidence of HER2-expressing brain metastases in patients with HER2-null breast cancer: a matched case analysis
por: Moss, Nelson S., et al.
Publicado: (2023)

Tumor Heterogeneity in Breast Cancer
por: Turashvili, Gulisa, et al.
Publicado: (2017)

Retrospective Evaluation of Somatic Alterations in Cell-Free DNA from Blood in Retinoblastoma
por: Abramson, David H., et al.
Publicado: (2021)

Splice Variants of Androgen Receptor and Prostate Cancer
por: Caffo, Orazio, et al.
Publicado: (2016)

Androgen receptor signaling regulates the transcriptome of prostate cancer cells by modulating global alternative splicing
por: Shah, Kalpit, et al.
Publicado: (2020)

Mutant-RB1 circulating tumor DNA in the blood of unilateral retinoblastoma patients: What happens during enucleation surgery: A pilot study
por: Abramson, David H., et al.
Publicado: (2023)

Comprehensive detection of germline variants by MSK-IMPACT, a clinical diagnostic platform for solid tumor molecular oncology and concurrent cancer predisposition testing
por: Cheng, Donavan T., et al.
Publicado: (2017)

Advances in managing breast cancer: a clinical update
por: Gucalp, Ayca, et al.
Publicado: (2014)

The genomic landscape of metastatic histologic special types of invasive breast cancer
por: Pareja, Fresia, et al.
Publicado: (2020)

Immunophenotype and Response to Immunotherapy of RET-Rearranged Lung Cancers
por: Offin, Michael, et al.
Publicado: (2019)

Androgen receptor splice variants activating the full-length receptor in mediating resistance to androgen-directed therapy
por: Cao, Bo, et al.
Publicado: (2014)

Expression of androgen receptor splice variants in clinical breast cancers
por: Hickey, Theresa E., et al.
Publicado: (2015)

Role of androgen receptor splice variants in prostate cancer metastasis
por: Xu, Jin, et al.
Publicado: (2016)

Efficacy and Safety of Gemcitabine With Trastuzumab and Pertuzumab After Prior Pertuzumab-Based Therapy Among Patients With Human Epidermal Growth Factor Receptor 2–Positive Metastatic Breast Cancer: A Phase 2 Clinical Trial
por: Iyengar, Neil M., et al.
Publicado: (2019)

Structure–function analysis of oncogenic EGFR Kinase Domain Duplication reveals insights into activation and a potential approach for therapeutic targeting
por: Du, Zhenfang, et al.
Publicado: (2021)

DNAJB1-PRKACA fusions occur in oncocytic pancreatic and biliary neoplasms and are not specific for fibrolamellar hepatocellular carcinoma
por: Vyas, Monika, et al.
Publicado: (2019)

Histone lysine demethylase KDM4B regulates the alternative splicing of the androgen receptor in response to androgen deprivation
por: Duan, Lingling, et al.
Publicado: (2019)

Ratio of the expression levels of androgen receptor splice variant 7 to androgen receptor in castration refractory prostate cancer
por: Sekine, Yoshitaka, et al.
Publicado: (2021)

Myeloid/lymphoid neoplasms with eosinophilia/basophilia and ETV6-ABL1 fusion: cell-of-origin and response to tyrosine kinase inhibition
por: Yao, Jinjuan, et al.
Publicado: (2020)

Androgen receptor splice variants and polycystic ovary syndrome: cause or effect?
por: Walters, Kirsty A, et al.
Publicado: (2016)

Androgen receptor splice variants and prostate cancer: From bench to bedside
por: Wadosky, Kristine M., et al.
Publicado: (2017)

Regulation of androgen receptor splice variant AR3 by PCGEM1
por: Zhang, Ziqiang, et al.
Publicado: (2016)

A case of KMT2A–SEPT9 fusion–associated acute megakaryoblastic leukemia
por: Forlenza, Christopher J., et al.
Publicado: (2018)

Spindle cell lesions of the breast: a diagnostic approach
por: Rakha, Emad A., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_uk3uel3q5sk07q1cg68njevppv