FOXP3/HAT1 Axis Controls Treg Infiltration in the Tumor Microenvironment by Inducing CCR4 Expression in Breast Cancer

Infiltrating T-regulatory cells in the tumor microenvironment is a key impediment to immunotherapy and is linked to a poor prognosis. We found that tumor-infiltrating Tregs express a higher expression of the chemokine receptor CCR4 than peripheral Tregs in breast cancer patients. CCL22 and CCL17 are...

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Detalles Bibliográficos
Autores principales: Sarkar, Tania, Dhar, Subhanki, Chakraborty, Dwaipayan, Pati, Subhadip, Bose, Sayantan, Panda, Abir K., Basak, Udit, Chakraborty, Sourio, Mukherjee, Sumon, Guin, Aharna, Jana, Kuladip, Sarkar, Diptendra K., Sa, Gaurisankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863663/
https://www.ncbi.nlm.nih.gov/pubmed/35222362
http://dx.doi.org/10.3389/fimmu.2022.740588

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863663/
https://www.ncbi.nlm.nih.gov/pubmed/35222362
http://dx.doi.org/10.3389/fimmu.2022.740588

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