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Exploring the MEN1 dependent modulation of caspase 8 and caspase 3 in human pancreatic and murine embryo fibroblast cells

MEN1 mutation causes pancreatic neuroendocrine neoplasia and benign malignancies of the parathyroid, the adrenal cortex and pituitary gland. The transcriptional activity of its product menin promotes the expression of genes deputed to several cellular mechanism including cell death. Here, we focused...

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Detalles Bibliográficos
Autores principales: Wagener, Nele, Buchholz, Malte, Bertolino, Philippe, Zhang, Chang X., Di Fazio, Pietro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863690/
https://www.ncbi.nlm.nih.gov/pubmed/34878630
http://dx.doi.org/10.1007/s10495-021-01700-1