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Challenges and Open Issues in Transcatheter Mitral Valve Implantation: Smooth Seas Do Not Make Skillful Sailors

According to the European and American guidelines, surgery represents the treatment of choice for mitral valve (MV) disease. However, a number of patients are deemed unsuitable for surgery due to a prohibitive/high operative risk. In such cases, transcatheter therapies aiming at MV repair have been...

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Autores principales: Russo, Giulio, Maisano, Francesco, Massaro, Gianluca, Terlizzese, Giuseppe, Mariano, Enrica, Bonanni, Michela, Matteucci, Andrea, Bezzeccheri, Andrea, Benedetto, Daniela, Chiricolo, Gaetano, Martuscelli, Eugenio, Sangiorgi, Giuseppe Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863742/
https://www.ncbi.nlm.nih.gov/pubmed/35224022
http://dx.doi.org/10.3389/fcvm.2021.738756
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author Russo, Giulio
Maisano, Francesco
Massaro, Gianluca
Terlizzese, Giuseppe
Mariano, Enrica
Bonanni, Michela
Matteucci, Andrea
Bezzeccheri, Andrea
Benedetto, Daniela
Chiricolo, Gaetano
Martuscelli, Eugenio
Sangiorgi, Giuseppe Massimo
author_facet Russo, Giulio
Maisano, Francesco
Massaro, Gianluca
Terlizzese, Giuseppe
Mariano, Enrica
Bonanni, Michela
Matteucci, Andrea
Bezzeccheri, Andrea
Benedetto, Daniela
Chiricolo, Gaetano
Martuscelli, Eugenio
Sangiorgi, Giuseppe Massimo
author_sort Russo, Giulio
collection PubMed
description According to the European and American guidelines, surgery represents the treatment of choice for mitral valve (MV) disease. However, a number of patients are deemed unsuitable for surgery due to a prohibitive/high operative risk. In such cases, transcatheter therapies aiming at MV repair have been proven to be a valuable alternative and have been recently introduced in the latest American guidelines on valvular heart disease. Indeed, percutaneous repair techniques, particularly transcatheter edge-to-edge, have gained a broad experience and demonstrated to be safe and effective. However, given the complexity and heterogeneity of MV anatomy and pathology, transcatheter MV implantation (TMVI) has grown as a possible alternative to percutaneous MV repair. Current data about TMVI are still limited and come from different settings: valve-in-native MV, valve-in-valve (ViV), valve-in-ring (ViR), and valve-in-mitral annular calcification. Preliminary data are promising although several open issues still need to be addressed. This paper provides a comprehensive review of the available devices in the different clinical settings, to discuss potentialities, limitations, and future directions for TMVI.
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spelling pubmed-88637422022-02-24 Challenges and Open Issues in Transcatheter Mitral Valve Implantation: Smooth Seas Do Not Make Skillful Sailors Russo, Giulio Maisano, Francesco Massaro, Gianluca Terlizzese, Giuseppe Mariano, Enrica Bonanni, Michela Matteucci, Andrea Bezzeccheri, Andrea Benedetto, Daniela Chiricolo, Gaetano Martuscelli, Eugenio Sangiorgi, Giuseppe Massimo Front Cardiovasc Med Cardiovascular Medicine According to the European and American guidelines, surgery represents the treatment of choice for mitral valve (MV) disease. However, a number of patients are deemed unsuitable for surgery due to a prohibitive/high operative risk. In such cases, transcatheter therapies aiming at MV repair have been proven to be a valuable alternative and have been recently introduced in the latest American guidelines on valvular heart disease. Indeed, percutaneous repair techniques, particularly transcatheter edge-to-edge, have gained a broad experience and demonstrated to be safe and effective. However, given the complexity and heterogeneity of MV anatomy and pathology, transcatheter MV implantation (TMVI) has grown as a possible alternative to percutaneous MV repair. Current data about TMVI are still limited and come from different settings: valve-in-native MV, valve-in-valve (ViV), valve-in-ring (ViR), and valve-in-mitral annular calcification. Preliminary data are promising although several open issues still need to be addressed. This paper provides a comprehensive review of the available devices in the different clinical settings, to discuss potentialities, limitations, and future directions for TMVI. Frontiers Media S.A. 2022-02-09 /pmc/articles/PMC8863742/ /pubmed/35224022 http://dx.doi.org/10.3389/fcvm.2021.738756 Text en Copyright © 2022 Russo, Maisano, Massaro, Terlizzese, Mariano, Bonanni, Matteucci, Bezzeccheri, Benedetto, Chiricolo, Martuscelli and Sangiorgi. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cardiovascular Medicine
Russo, Giulio
Maisano, Francesco
Massaro, Gianluca
Terlizzese, Giuseppe
Mariano, Enrica
Bonanni, Michela
Matteucci, Andrea
Bezzeccheri, Andrea
Benedetto, Daniela
Chiricolo, Gaetano
Martuscelli, Eugenio
Sangiorgi, Giuseppe Massimo
Challenges and Open Issues in Transcatheter Mitral Valve Implantation: Smooth Seas Do Not Make Skillful Sailors
title Challenges and Open Issues in Transcatheter Mitral Valve Implantation: Smooth Seas Do Not Make Skillful Sailors
title_full Challenges and Open Issues in Transcatheter Mitral Valve Implantation: Smooth Seas Do Not Make Skillful Sailors
title_fullStr Challenges and Open Issues in Transcatheter Mitral Valve Implantation: Smooth Seas Do Not Make Skillful Sailors
title_full_unstemmed Challenges and Open Issues in Transcatheter Mitral Valve Implantation: Smooth Seas Do Not Make Skillful Sailors
title_short Challenges and Open Issues in Transcatheter Mitral Valve Implantation: Smooth Seas Do Not Make Skillful Sailors
title_sort challenges and open issues in transcatheter mitral valve implantation: smooth seas do not make skillful sailors
topic Cardiovascular Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863742/
https://www.ncbi.nlm.nih.gov/pubmed/35224022
http://dx.doi.org/10.3389/fcvm.2021.738756
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