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An enhanced triple fluorescence flow-cytometry-based assay shows differential activation of the Notch signaling pathway by human papillomavirus E6 proteins

Human papillomaviruses are DNA tumor viruses. A persistent infection with high-risk HPV types is the necessary risk factor for the development of anogenital carcinoma. The E6 protein is a viral oncoprotein that directly interacts with different cellular regulatory proteins mainly affecting the cell...

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Detalles Bibliográficos
Autores principales: Lim, JiaWen, Straub, Elke, Stubenrauch, Frank, Iftner, Thomas, Schindler, Michael, Simon, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863805/
https://www.ncbi.nlm.nih.gov/pubmed/35194094
http://dx.doi.org/10.1038/s41598-022-06922-0