Long noncoding RNA SNHG1 silencing accelerates hepatocyte-like cell differentiation of bone marrow-derived mesenchymal stem cells to alleviate cirrhosis via the microRNA-15a/SMURF1/UVRAG axis

Bone marrow-derived mesenchymal stem cells (BMSCs) can differentiate into hepatocyte-like cells (HLCs) to attenuate cirrhosis. Long noncoding RNA (lncRNA) SNHG1 has been demonstrated to orchestrate BMSC differentiation, whereas its role in cirrhosis remains elusive. Therefore, this study was perform...

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Detalles Bibliográficos
Autores principales: Sun, Jia, Sun, Xuedong, Hu, Sean, Wang, Maoqiang, Ma, Na, Chen, Junhui, Duan, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863836/
https://www.ncbi.nlm.nih.gov/pubmed/35194023
http://dx.doi.org/10.1038/s41420-022-00850-8

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