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Mediastinal Fibrosarcoma in a Dog–Case Report

This represents the first published case report of mediastinal fibrosarcoma in a dog. An 8-year-old male neutered mixed breed dog was presented for evaluation of lethargy and increased panting. Thoracic focused assessment with sonography for trauma revealed moderate pleural effusion. Thoracic radiog...

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Autores principales: McGrath, Alysha M., Salyer, Sarah A., Seelmann, Amanda, Lundberg, Alycen P., Leonard, Melissa R., Lorbach, Joshua N., Lumbrezer-Johnson, Sarah, Hostnik, Eric T., Tremolada, Giovanni, Lapsley, Janis, Selmic, Laura E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863873/
https://www.ncbi.nlm.nih.gov/pubmed/35224085
http://dx.doi.org/10.3389/fvets.2022.820956
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author McGrath, Alysha M.
Salyer, Sarah A.
Seelmann, Amanda
Lundberg, Alycen P.
Leonard, Melissa R.
Lorbach, Joshua N.
Lumbrezer-Johnson, Sarah
Hostnik, Eric T.
Tremolada, Giovanni
Lapsley, Janis
Selmic, Laura E.
author_facet McGrath, Alysha M.
Salyer, Sarah A.
Seelmann, Amanda
Lundberg, Alycen P.
Leonard, Melissa R.
Lorbach, Joshua N.
Lumbrezer-Johnson, Sarah
Hostnik, Eric T.
Tremolada, Giovanni
Lapsley, Janis
Selmic, Laura E.
author_sort McGrath, Alysha M.
collection PubMed
description This represents the first published case report of mediastinal fibrosarcoma in a dog. An 8-year-old male neutered mixed breed dog was presented for evaluation of lethargy and increased panting. Thoracic focused assessment with sonography for trauma revealed moderate pleural effusion. Thoracic radiograph findings were suggestive of a cranial mediastinal mass. Computed tomography revealed a mass within the right ventral aspect of the cranial mediastinum. On surgical exploration, a cranial mediastinal mass with an adhesion to the right cranial lung lobe was identified and removed en-bloc using a vessel sealant device and requiring a partial lung lobectomy. Histopathology results described the cranial mediastinal mass as fibrosarcoma with reactive mesothelial cells identified within the sternal lymph node. The patient was treated with systemic chemotherapy following surgical removal. To date, the dog has survived 223 days following diagnosis with recurrence noted 161 days following diagnosis and radiation therapy was initiated. Primary cranial mediastinal fibrosarcoma while a seemingly rare cause of thoracic pathology in dogs, should be considered in the differential diagnosis for a cranial mediastinal mass.
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spelling pubmed-88638732022-02-24 Mediastinal Fibrosarcoma in a Dog–Case Report McGrath, Alysha M. Salyer, Sarah A. Seelmann, Amanda Lundberg, Alycen P. Leonard, Melissa R. Lorbach, Joshua N. Lumbrezer-Johnson, Sarah Hostnik, Eric T. Tremolada, Giovanni Lapsley, Janis Selmic, Laura E. Front Vet Sci Veterinary Science This represents the first published case report of mediastinal fibrosarcoma in a dog. An 8-year-old male neutered mixed breed dog was presented for evaluation of lethargy and increased panting. Thoracic focused assessment with sonography for trauma revealed moderate pleural effusion. Thoracic radiograph findings were suggestive of a cranial mediastinal mass. Computed tomography revealed a mass within the right ventral aspect of the cranial mediastinum. On surgical exploration, a cranial mediastinal mass with an adhesion to the right cranial lung lobe was identified and removed en-bloc using a vessel sealant device and requiring a partial lung lobectomy. Histopathology results described the cranial mediastinal mass as fibrosarcoma with reactive mesothelial cells identified within the sternal lymph node. The patient was treated with systemic chemotherapy following surgical removal. To date, the dog has survived 223 days following diagnosis with recurrence noted 161 days following diagnosis and radiation therapy was initiated. Primary cranial mediastinal fibrosarcoma while a seemingly rare cause of thoracic pathology in dogs, should be considered in the differential diagnosis for a cranial mediastinal mass. Frontiers Media S.A. 2022-02-09 /pmc/articles/PMC8863873/ /pubmed/35224085 http://dx.doi.org/10.3389/fvets.2022.820956 Text en Copyright © 2022 McGrath, Salyer, Seelmann, Lundberg, Leonard, Lorbach, Lumbrezer-Johnson, Hostnik, Tremolada, Lapsley and Selmic. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Veterinary Science
McGrath, Alysha M.
Salyer, Sarah A.
Seelmann, Amanda
Lundberg, Alycen P.
Leonard, Melissa R.
Lorbach, Joshua N.
Lumbrezer-Johnson, Sarah
Hostnik, Eric T.
Tremolada, Giovanni
Lapsley, Janis
Selmic, Laura E.
Mediastinal Fibrosarcoma in a Dog–Case Report
title Mediastinal Fibrosarcoma in a Dog–Case Report
title_full Mediastinal Fibrosarcoma in a Dog–Case Report
title_fullStr Mediastinal Fibrosarcoma in a Dog–Case Report
title_full_unstemmed Mediastinal Fibrosarcoma in a Dog–Case Report
title_short Mediastinal Fibrosarcoma in a Dog–Case Report
title_sort mediastinal fibrosarcoma in a dog–case report
topic Veterinary Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863873/
https://www.ncbi.nlm.nih.gov/pubmed/35224085
http://dx.doi.org/10.3389/fvets.2022.820956
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