Cargando…
A synthetic protein as efficient multitarget regulator against complement over-activation
The complement system constitutes the innate defense against pathogens. Its dysregulation leads to diseases and is a critical determinant in many viral infections, e.g., COVID-19. Factor H (FH) is the main regulator of the alternative pathway of complement activation and could be a therapy to restor...
Autores principales: | Ruiz-Molina, Natalia, Parsons, Juliana, Müller, Madeleine, Hoernstein, Sebastian N. W., Bohlender, Lennard L., Pumple, Steffen, Zipfel, Peter F., Häffner, Karsten, Reski, Ralf, Decker, Eva L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863895/ https://www.ncbi.nlm.nih.gov/pubmed/35194132 http://dx.doi.org/10.1038/s42003-022-03094-5 |
Ejemplares similares
-
Recombinant Production of MFHR1, A Novel Synthetic Multitarget Complement Inhibitor, in Moss Bioreactors
por: Top, Oguz, et al.
Publicado: (2019) -
Unexpected Arabinosylation after Humanization of Plant Protein N-Glycosylation
por: Bohlender, Lennard L., et al.
Publicado: (2022) -
Structural modelling of human complement FHR1 and two of its synthetic derivatives provides insight into their in-vivo functions
por: Ruiz-Molina, Natalia, et al.
Publicado: (2023) -
Stable Protein Sialylation in Physcomitrella
por: Bohlender, Lennard L., et al.
Publicado: (2020) -
Glyco-engineering for biopharmaceutical production in moss bioreactors
por: Decker, Eva L., et al.
Publicado: (2014)