The Role and Research Progress of Inhibitor of Differentiation 1 in Atherosclerosis

Inhibitor of differentiation 1 has a helix-loop-helix (HLH) structure, belongs to a class of molecules known as the HLH trans-acting factor family, and plays an important role in advancing the cell cycle, promoting cell proliferation and inhibiting cell differentiation. Recent studies have confirmed...

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Autores principales: Qiu, Jun, Li, Youhong, Wang, BingYu, Sun, XinYi, Qian, Dingding, Ying, Yuchen, Zhou, Jianqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2022
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863915/
https://www.ncbi.nlm.nih.gov/pubmed/35049366
http://dx.doi.org/10.1089/dna.2021.0745
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author Qiu, Jun
Li, Youhong
Wang, BingYu
Sun, XinYi
Qian, Dingding
Ying, Yuchen
Zhou, Jianqing
author_facet Qiu, Jun
Li, Youhong
Wang, BingYu
Sun, XinYi
Qian, Dingding
Ying, Yuchen
Zhou, Jianqing
author_sort Qiu, Jun
collection PubMed
description Inhibitor of differentiation 1 has a helix-loop-helix (HLH) structure, belongs to a class of molecules known as the HLH trans-acting factor family, and plays an important role in advancing the cell cycle, promoting cell proliferation and inhibiting cell differentiation. Recent studies have confirmed that inhibitor of differentiation 1 plays an important role in the endothelial-mesenchymal transition of vascular endothelial cells, angiogenesis, reendothelialization after injury, and the formation and rupture of atherosclerotic plaques. An in-depth understanding of the role of inhibitor of differentiation 1 in atherosclerosis will provide new ideas and strategies for the treatment of related diseases.
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spelling pubmed-88639152022-02-23 The Role and Research Progress of Inhibitor of Differentiation 1 in Atherosclerosis Qiu, Jun Li, Youhong Wang, BingYu Sun, XinYi Qian, Dingding Ying, Yuchen Zhou, Jianqing DNA Cell Biol Reviews Inhibitor of differentiation 1 has a helix-loop-helix (HLH) structure, belongs to a class of molecules known as the HLH trans-acting factor family, and plays an important role in advancing the cell cycle, promoting cell proliferation and inhibiting cell differentiation. Recent studies have confirmed that inhibitor of differentiation 1 plays an important role in the endothelial-mesenchymal transition of vascular endothelial cells, angiogenesis, reendothelialization after injury, and the formation and rupture of atherosclerotic plaques. An in-depth understanding of the role of inhibitor of differentiation 1 in atherosclerosis will provide new ideas and strategies for the treatment of related diseases. Mary Ann Liebert, Inc., publishers 2022-02-01 2022-02-09 /pmc/articles/PMC8863915/ /pubmed/35049366 http://dx.doi.org/10.1089/dna.2021.0745 Text en © Jun Qiu et al. 2022; Published by Mary Ann Liebert, Inc. https://creativecommons.org/licenses/by/4.0/This Open Access article is distributed under the terms of the Creative Commons License [CC-BY] (http://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Reviews
Qiu, Jun
Li, Youhong
Wang, BingYu
Sun, XinYi
Qian, Dingding
Ying, Yuchen
Zhou, Jianqing
The Role and Research Progress of Inhibitor of Differentiation 1 in Atherosclerosis
title The Role and Research Progress of Inhibitor of Differentiation 1 in Atherosclerosis
title_full The Role and Research Progress of Inhibitor of Differentiation 1 in Atherosclerosis
title_fullStr The Role and Research Progress of Inhibitor of Differentiation 1 in Atherosclerosis
title_full_unstemmed The Role and Research Progress of Inhibitor of Differentiation 1 in Atherosclerosis
title_short The Role and Research Progress of Inhibitor of Differentiation 1 in Atherosclerosis
title_sort role and research progress of inhibitor of differentiation 1 in atherosclerosis
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863915/
https://www.ncbi.nlm.nih.gov/pubmed/35049366
http://dx.doi.org/10.1089/dna.2021.0745
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