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Spatial Multiomics Analysis Reveals Only Minor Genetic and Epigenetic Changes in Human Liver Cancer Stem-Like Cells Compared With Other Tumor Parenchymal Cells

Cancer stem cells (CSCs) usually account for a very small tumor cell population but play pivotal roles in human cancer development and recurrence. A fundamental question in cancer biology is what genetic and epigenetic changes occur in CSCs. Here we show that the in-situ global levels of DNA cytosin...

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Detalles Bibliográficos
Autores principales:	Liu, Dan, Li, Hong, Dong, Hui, Qu, Mincheng, Yang, Liguang, Chen, Lina, Li, Yixue, Wang, Hongyang, He, Yufei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863946/ https://www.ncbi.nlm.nih.gov/pubmed/35223840 http://dx.doi.org/10.3389/fcell.2022.810687

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