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Pathogenesis of vaccine-induced immune thrombotic thrombocytopenia (VITT)

Vaccine-induced immune thrombotic thrombocytopenia (VITT; synonym, thrombosis with thrombocytopenia syndrome, is associated with high-titer immunoglobulin G antibodies directed against platelet factor 4 (PF4). These antibodies activate platelets via platelet FcγIIa receptors, with platelet activatio...

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Detalles Bibliográficos
Autores principales: Greinacher, Andreas, Schönborn, Linda, Siegerist, Florian, Steil, Leif, Palankar, Raghavendra, Handtke, Stefan, Reder, Alexander, Thiele, Thomas, Aurich, Konstanze, Methling, Karen, Lalk, Michael, Völker, Uwe, Endlich, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863951/
https://www.ncbi.nlm.nih.gov/pubmed/35512907
http://dx.doi.org/10.1053/j.seminhematol.2022.02.004

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