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Degradation of DRAK1 by CUL3/SPOP E3 Ubiquitin ligase promotes tumor growth of paclitaxel-resistant cervical cancer cells

Despite favorable responses to initial chemotherapy, drug resistance is a major cause limiting chemotherapeutic efficacy in many advanced cancers. However, mechanisms that drive drug-specific resistance in chemotherapy for patients with advanced cancers are still unclear. Here, we report a unique ro...

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Detalles Bibliográficos
Autores principales:	Pang, Kyoungwha, Lee, Jihee, Kim, Junil, Park, Jinah, Park, Yuna, Hong, Eunji, An, Haein, Ooshima, Akira, Son, Minjung, Park, Kyung-Soon, Cho, Jae-Hyun, Lee, Cheol, Song, Yong Sang, Yang, Kyung-Min, Kim, Seong-Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863983/ https://www.ncbi.nlm.nih.gov/pubmed/35194034 http://dx.doi.org/10.1038/s41419-022-04619-w

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