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Cardiac contractility modulation ameliorates myocardial metabolic remodeling in a rabbit model of chronic heart failure through activation of AMPK and PPAR-α pathway
Metabolic remodeling contributes to the pathological process of heart failure (HF). We explored the effects of cardiac contractility modulation (CCM) on myocardial metabolic remodeling in the rabbit model with HF. The HF in rabbit model was established by pressure uploading and then CCM was applied....
Autores principales: | Zhang, Feifei, Liu, Litian, Xie, Yuetao, Wang, Jiaqi, Chen, Xuefeng, Zheng, Shihang, Li, Yingxiao, Dang, Yi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
De Gruyter
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864057/ https://www.ncbi.nlm.nih.gov/pubmed/35799598 http://dx.doi.org/10.1515/med-2022-0415 |
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