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Roburic Acid Targets TNF to Inhibit the NF-κB Signaling Pathway and Suppress Human Colorectal Cancer Cell Growth

Tumor necrosis factor (TNF)-stimulated nuclear factor-kappa B (NF-κB) signaling plays very crucial roles in cancer development and progression, and represents a potential target for drug discovery. Roburic acid is a newly discovered tetracyclic triterpene acid isolated from oak galls and exhibits an...

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Detalles Bibliográficos
Autores principales: Xu, Huanhuan, Liu, Titi, Li, Jin, Chen, Fei, Xu, Jing, Hu, Lihong, Jiang, Li, Xiang, Zemin, Wang, Xuanjun, Sheng, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864141/
https://www.ncbi.nlm.nih.gov/pubmed/35222445
http://dx.doi.org/10.3389/fimmu.2022.853165