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An Uncommon Case of Dulaglutide-Related Morbilliform Drug Eruption
Dulaglutide is a once-weekly injectable glucagon-like peptide-1 (GLP-1) receptor agonist that has shown a durable glycemic efficacy as well as beneficial effects on body weight and major adverse cardiovascular events (MACE) outcomes, making it an important option for the treatment of type 2 diabetes...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864188/ https://www.ncbi.nlm.nih.gov/pubmed/35223310 http://dx.doi.org/10.7759/cureus.21536 |
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author | Kyriakos, Georgios Diamantis, Evangelos Memi, Eleni Elefsiniotis, Ioannis |
author_facet | Kyriakos, Georgios Diamantis, Evangelos Memi, Eleni Elefsiniotis, Ioannis |
author_sort | Kyriakos, Georgios |
collection | PubMed |
description | Dulaglutide is a once-weekly injectable glucagon-like peptide-1 (GLP-1) receptor agonist that has shown a durable glycemic efficacy as well as beneficial effects on body weight and major adverse cardiovascular events (MACE) outcomes, making it an important option for the treatment of type 2 diabetes. Common side effects of dulaglutide include nausea, diarrhea, and abdominal distension, and these are usually mild to moderate in severity and tend to diminish over time. Morbilliform drug eruptions to dulaglutide are very rare, with only one case reported until now. We report another case of dulaglutide-morbilliform drug eruption to alert the attending physicians that dulaglutide-related adverse skin reactions should be kept in mind as generalized use of dulaglutide and other GLP-1 receptor agonists are expected to remain in widespread clinical use in the future. |
format | Online Article Text |
id | pubmed-8864188 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-88641882022-02-26 An Uncommon Case of Dulaglutide-Related Morbilliform Drug Eruption Kyriakos, Georgios Diamantis, Evangelos Memi, Eleni Elefsiniotis, Ioannis Cureus Dermatology Dulaglutide is a once-weekly injectable glucagon-like peptide-1 (GLP-1) receptor agonist that has shown a durable glycemic efficacy as well as beneficial effects on body weight and major adverse cardiovascular events (MACE) outcomes, making it an important option for the treatment of type 2 diabetes. Common side effects of dulaglutide include nausea, diarrhea, and abdominal distension, and these are usually mild to moderate in severity and tend to diminish over time. Morbilliform drug eruptions to dulaglutide are very rare, with only one case reported until now. We report another case of dulaglutide-morbilliform drug eruption to alert the attending physicians that dulaglutide-related adverse skin reactions should be kept in mind as generalized use of dulaglutide and other GLP-1 receptor agonists are expected to remain in widespread clinical use in the future. Cureus 2022-01-23 /pmc/articles/PMC8864188/ /pubmed/35223310 http://dx.doi.org/10.7759/cureus.21536 Text en Copyright © 2022, Kyriakos et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Dermatology Kyriakos, Georgios Diamantis, Evangelos Memi, Eleni Elefsiniotis, Ioannis An Uncommon Case of Dulaglutide-Related Morbilliform Drug Eruption |
title | An Uncommon Case of Dulaglutide-Related Morbilliform Drug Eruption |
title_full | An Uncommon Case of Dulaglutide-Related Morbilliform Drug Eruption |
title_fullStr | An Uncommon Case of Dulaglutide-Related Morbilliform Drug Eruption |
title_full_unstemmed | An Uncommon Case of Dulaglutide-Related Morbilliform Drug Eruption |
title_short | An Uncommon Case of Dulaglutide-Related Morbilliform Drug Eruption |
title_sort | uncommon case of dulaglutide-related morbilliform drug eruption |
topic | Dermatology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864188/ https://www.ncbi.nlm.nih.gov/pubmed/35223310 http://dx.doi.org/10.7759/cureus.21536 |
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