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An Uncommon Case of Dulaglutide-Related Morbilliform Drug Eruption

Dulaglutide is a once-weekly injectable glucagon-like peptide-1 (GLP-1) receptor agonist that has shown a durable glycemic efficacy as well as beneficial effects on body weight and major adverse cardiovascular events (MACE) outcomes, making it an important option for the treatment of type 2 diabetes...

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Autores principales: Kyriakos, Georgios, Diamantis, Evangelos, Memi, Eleni, Elefsiniotis, Ioannis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864188/
https://www.ncbi.nlm.nih.gov/pubmed/35223310
http://dx.doi.org/10.7759/cureus.21536
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author Kyriakos, Georgios
Diamantis, Evangelos
Memi, Eleni
Elefsiniotis, Ioannis
author_facet Kyriakos, Georgios
Diamantis, Evangelos
Memi, Eleni
Elefsiniotis, Ioannis
author_sort Kyriakos, Georgios
collection PubMed
description Dulaglutide is a once-weekly injectable glucagon-like peptide-1 (GLP-1) receptor agonist that has shown a durable glycemic efficacy as well as beneficial effects on body weight and major adverse cardiovascular events (MACE) outcomes, making it an important option for the treatment of type 2 diabetes. Common side effects of dulaglutide include nausea, diarrhea, and abdominal distension, and these are usually mild to moderate in severity and tend to diminish over time. Morbilliform drug eruptions to dulaglutide are very rare, with only one case reported until now. We report another case of dulaglutide-morbilliform drug eruption to alert the attending physicians that dulaglutide-related adverse skin reactions should be kept in mind as generalized use of dulaglutide and other GLP-1 receptor agonists are expected to remain in widespread clinical use in the future.
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spelling pubmed-88641882022-02-26 An Uncommon Case of Dulaglutide-Related Morbilliform Drug Eruption Kyriakos, Georgios Diamantis, Evangelos Memi, Eleni Elefsiniotis, Ioannis Cureus Dermatology Dulaglutide is a once-weekly injectable glucagon-like peptide-1 (GLP-1) receptor agonist that has shown a durable glycemic efficacy as well as beneficial effects on body weight and major adverse cardiovascular events (MACE) outcomes, making it an important option for the treatment of type 2 diabetes. Common side effects of dulaglutide include nausea, diarrhea, and abdominal distension, and these are usually mild to moderate in severity and tend to diminish over time. Morbilliform drug eruptions to dulaglutide are very rare, with only one case reported until now. We report another case of dulaglutide-morbilliform drug eruption to alert the attending physicians that dulaglutide-related adverse skin reactions should be kept in mind as generalized use of dulaglutide and other GLP-1 receptor agonists are expected to remain in widespread clinical use in the future. Cureus 2022-01-23 /pmc/articles/PMC8864188/ /pubmed/35223310 http://dx.doi.org/10.7759/cureus.21536 Text en Copyright © 2022, Kyriakos et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Dermatology
Kyriakos, Georgios
Diamantis, Evangelos
Memi, Eleni
Elefsiniotis, Ioannis
An Uncommon Case of Dulaglutide-Related Morbilliform Drug Eruption
title An Uncommon Case of Dulaglutide-Related Morbilliform Drug Eruption
title_full An Uncommon Case of Dulaglutide-Related Morbilliform Drug Eruption
title_fullStr An Uncommon Case of Dulaglutide-Related Morbilliform Drug Eruption
title_full_unstemmed An Uncommon Case of Dulaglutide-Related Morbilliform Drug Eruption
title_short An Uncommon Case of Dulaglutide-Related Morbilliform Drug Eruption
title_sort uncommon case of dulaglutide-related morbilliform drug eruption
topic Dermatology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864188/
https://www.ncbi.nlm.nih.gov/pubmed/35223310
http://dx.doi.org/10.7759/cureus.21536
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