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IFN-β Deficiency Results in Fatal or Demyelinating Disease in C57BL/6 Mice Infected With Theiler’s Murine Encephalomyelitis Viruses

Type I Interferons (IFN-I) are important inducers of the antiviral immune response and immune modulators. IFN-β is the most highly expressed IFN-I in the central nervous system (CNS). The infection of SJL mice with the BeAn or the DA strain of Theiler’s murine encephalomyelitis virus (TMEV) results...

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Detalles Bibliográficos
Autores principales: Bühler, Melanie, Runft, Sandra, Li, Dandan, Götting, Jasper, Detje, Claudia N., Nippold, Vanessa, Stoff, Melanie, Beineke, Andreas, Schulz, Thomas, Kalinke, Ulrich, Baumgärtner, Wolfgang, Gerhauser, Ingo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864290/
https://www.ncbi.nlm.nih.gov/pubmed/35222374
http://dx.doi.org/10.3389/fimmu.2022.786940

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