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IFN-β Deficiency Results in Fatal or Demyelinating Disease in C57BL/6 Mice Infected With Theiler’s Murine Encephalomyelitis Viruses
Type I Interferons (IFN-I) are important inducers of the antiviral immune response and immune modulators. IFN-β is the most highly expressed IFN-I in the central nervous system (CNS). The infection of SJL mice with the BeAn or the DA strain of Theiler’s murine encephalomyelitis virus (TMEV) results...
Autores principales: | Bühler, Melanie, Runft, Sandra, Li, Dandan, Götting, Jasper, Detje, Claudia N., Nippold, Vanessa, Stoff, Melanie, Beineke, Andreas, Schulz, Thomas, Kalinke, Ulrich, Baumgärtner, Wolfgang, Gerhauser, Ingo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864290/ https://www.ncbi.nlm.nih.gov/pubmed/35222374 http://dx.doi.org/10.3389/fimmu.2022.786940 |
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