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Efanesoctocog alfa for hemophilia A: results from a phase 1 repeat-dose study

Efanesoctocog alfa (rFVIIIFc-VWF-XTEN; BIVV001) is a new class of factor VIII (FVIII) replacement that breaks the von Willebrand factor–imposed FVIII half-life ceiling. In a phase 1/2a study, single-dose efanesoctocog alfa was well tolerated, and no safety concerns were identified. We evaluated the...

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Detalles Bibliográficos
Autores principales:	Lissitchkov, Toshko, Willemze, Annemieke, Katragadda, Suresh, Rice, Kara, Poloskey, Stacey, Benson, Craig
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Hematology 2022
Materias:	Clinical Trials and Observations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864644/ https://www.ncbi.nlm.nih.gov/pubmed/34794179 http://dx.doi.org/10.1182/bloodadvances.2021006119

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