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Protection of nontarget structures in prostatic artery embolization

OBJECTIVE: To describe the efficacy and safety of protective embolization during prostatic artery embolization, as well as to discuss its clinical relevance. MATERIALS AND METHODS: This was a retrospective, observational, single-center study including 39 patients who underwent prostatic artery embol...

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Autores principales: Pilan, Bruna Ferreira, de Assis, André Moreira, Moreira, Airton Mota, Rodrigues, Vanessa Cristina de Paula, Carnevale, Francisco Cesar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Publicação do Colégio Brasileiro de Radiologia e Diagnóstico por Imagem 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864683/
https://www.ncbi.nlm.nih.gov/pubmed/35210658
http://dx.doi.org/10.1590/0100-3984.2021.0021
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author Pilan, Bruna Ferreira
de Assis, André Moreira
Moreira, Airton Mota
Rodrigues, Vanessa Cristina de Paula
Carnevale, Francisco Cesar
author_facet Pilan, Bruna Ferreira
de Assis, André Moreira
Moreira, Airton Mota
Rodrigues, Vanessa Cristina de Paula
Carnevale, Francisco Cesar
author_sort Pilan, Bruna Ferreira
collection PubMed
description OBJECTIVE: To describe the efficacy and safety of protective embolization during prostatic artery embolization, as well as to discuss its clinical relevance. MATERIALS AND METHODS: This was a retrospective, observational, single-center study including 39 patients who underwent prostatic artery embolization to treat lower urinary tract symptoms related to benign prostatic hyperplasia between June 2008 and March 2018. Follow-up evaluations, performed at 3 and 12 months after the procedure, included determination of the International Prostate Symptom Score, a quality of life score, and prostate-specific antigen levels, as well as ultrasound, magnetic resonance imaging, and uroflowmetry. RESULTS: Protective embolization was performed in 45 arteries: in the middle rectal artery in 19 (42.2%); in the accessory internal pudendal artery in 11 (24.4%); in an internal pudendal artery anastomosis in 10 (22.2%); in the superior vesical artery in four (8.9%); and in the obturator artery in one (2.2%). There was one case of nontarget embolization leading to a penile ulcer, which was attributed to reflux of microspheres to an unprotected artery. There were no complications related to the protected branches. All of the patients showed significant improvement in all of the outcomes studied (p < 0.05), and none reported worsening of sexual function during follow-up. CONCLUSION: Protective embolization can reduce nontarget embolization during prostatic artery embolization without affecting the results of the procedure. In addition, no adverse events other than those expected or previously reported were observed. Therefore, protective embolization of pudendal region is safe.
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spelling pubmed-88646832022-02-23 Protection of nontarget structures in prostatic artery embolization Pilan, Bruna Ferreira de Assis, André Moreira Moreira, Airton Mota Rodrigues, Vanessa Cristina de Paula Carnevale, Francisco Cesar Radiol Bras Original Article OBJECTIVE: To describe the efficacy and safety of protective embolization during prostatic artery embolization, as well as to discuss its clinical relevance. MATERIALS AND METHODS: This was a retrospective, observational, single-center study including 39 patients who underwent prostatic artery embolization to treat lower urinary tract symptoms related to benign prostatic hyperplasia between June 2008 and March 2018. Follow-up evaluations, performed at 3 and 12 months after the procedure, included determination of the International Prostate Symptom Score, a quality of life score, and prostate-specific antigen levels, as well as ultrasound, magnetic resonance imaging, and uroflowmetry. RESULTS: Protective embolization was performed in 45 arteries: in the middle rectal artery in 19 (42.2%); in the accessory internal pudendal artery in 11 (24.4%); in an internal pudendal artery anastomosis in 10 (22.2%); in the superior vesical artery in four (8.9%); and in the obturator artery in one (2.2%). There was one case of nontarget embolization leading to a penile ulcer, which was attributed to reflux of microspheres to an unprotected artery. There were no complications related to the protected branches. All of the patients showed significant improvement in all of the outcomes studied (p < 0.05), and none reported worsening of sexual function during follow-up. CONCLUSION: Protective embolization can reduce nontarget embolization during prostatic artery embolization without affecting the results of the procedure. In addition, no adverse events other than those expected or previously reported were observed. Therefore, protective embolization of pudendal region is safe. Publicação do Colégio Brasileiro de Radiologia e Diagnóstico por Imagem 2022 /pmc/articles/PMC8864683/ /pubmed/35210658 http://dx.doi.org/10.1590/0100-3984.2021.0021 Text en https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Pilan, Bruna Ferreira
de Assis, André Moreira
Moreira, Airton Mota
Rodrigues, Vanessa Cristina de Paula
Carnevale, Francisco Cesar
Protection of nontarget structures in prostatic artery embolization
title Protection of nontarget structures in prostatic artery embolization
title_full Protection of nontarget structures in prostatic artery embolization
title_fullStr Protection of nontarget structures in prostatic artery embolization
title_full_unstemmed Protection of nontarget structures in prostatic artery embolization
title_short Protection of nontarget structures in prostatic artery embolization
title_sort protection of nontarget structures in prostatic artery embolization
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864683/
https://www.ncbi.nlm.nih.gov/pubmed/35210658
http://dx.doi.org/10.1590/0100-3984.2021.0021
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