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Challenges in the clinical development pathway for triple and multiple drug combinations in the treatment of uncomplicated falciparum malaria

The addition of a third anti-malarial drug matching the pharmacokinetic characteristics of the slowly eliminated partner drug in artemisinin-based combination therapy (ACT) has been proposed as new therapeutic paradigm for the treatment of uncomplicated falciparum malaria. These triple artemisinin-b...

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Detalles Bibliográficos
Autores principales:	Bassat, Quique, Maïga-Ascofaré, Oumou, May, Jürgen, Clain, Jerôme, Mombo-Ngoma, Ghyslain, Groger, Mirjam, Adegnika, Ayôla A., Agobé, Jean-Claude Dejon, Djimde, Abdoulaye, Mischlinger, Johannes, Ramharter, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Opinion
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864855/ https://www.ncbi.nlm.nih.gov/pubmed/35193586 http://dx.doi.org/10.1186/s12936-022-04079-9

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