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Physical activity specifically evokes release of cell-free DNA from granulocytes thereby affecting liquid biopsy

Physical activity impacts immune homeostasis and leads to rapid and marked increase in cell-free DNA (cfDNA). However, the origin of cfDNA during exercise remains elusive and it is unknown if physical activity could improve or interfere with methylation based liquid biopsy. We analyzed the methylati...

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Detalles Bibliográficos
Autores principales: Neuberger, Elmo W. I., Sontag, Stephanie, Brahmer, Alexandra, Philippi, Keito F. A., Radsak, Markus P., Wagner, Wolfgang, Simon, Perikles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864902/
https://www.ncbi.nlm.nih.gov/pubmed/35193681
http://dx.doi.org/10.1186/s13148-022-01245-3