The value of electrostatic potentials of the spike receptor binding and N-terminal domains in addressing transmissibility and infectivity of SARS-CoV-2 variants of concern

Comparison of the surface electrostatic potential of the N-terminal (NTD) and the Receptor Binding Domains (RBD) of the Wuhan and Omicron Spikes. The entire Spikes are represented with transparent ribbon models. Only the NTD and RBD surfaces of the chain A are represented. Domain net charges are rep...

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Autores principales: Pascarella, Stefano, Ciccozzi, Massimo, Bianchi, Martina, Benvenuto, Domenico, Cauda, Roberto, Cassone, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Infection Association. Published by Elsevier Ltd. 2022
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864947/
https://www.ncbi.nlm.nih.gov/pubmed/35218789
http://dx.doi.org/10.1016/j.jinf.2022.02.023
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author Pascarella, Stefano
Ciccozzi, Massimo
Bianchi, Martina
Benvenuto, Domenico
Cauda, Roberto
Cassone, Antonio
author_facet Pascarella, Stefano
Ciccozzi, Massimo
Bianchi, Martina
Benvenuto, Domenico
Cauda, Roberto
Cassone, Antonio
author_sort Pascarella, Stefano
collection PubMed
description Comparison of the surface electrostatic potential of the N-terminal (NTD) and the Receptor Binding Domains (RBD) of the Wuhan and Omicron Spikes. The entire Spikes are represented with transparent ribbon models. Only the NTD and RBD surfaces of the chain A are represented. Domain net charges are reported within parenthesis beside the domain labels. Surface color ranges from -5.0 (red) to + 5.0 (blue) kT/e. [Figure: see text]
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spelling pubmed-88649472022-02-24 The value of electrostatic potentials of the spike receptor binding and N-terminal domains in addressing transmissibility and infectivity of SARS-CoV-2 variants of concern Pascarella, Stefano Ciccozzi, Massimo Bianchi, Martina Benvenuto, Domenico Cauda, Roberto Cassone, Antonio J Infect Letter to the Editor Comparison of the surface electrostatic potential of the N-terminal (NTD) and the Receptor Binding Domains (RBD) of the Wuhan and Omicron Spikes. The entire Spikes are represented with transparent ribbon models. Only the NTD and RBD surfaces of the chain A are represented. Domain net charges are reported within parenthesis beside the domain labels. Surface color ranges from -5.0 (red) to + 5.0 (blue) kT/e. [Figure: see text] The British Infection Association. Published by Elsevier Ltd. 2022-05 2022-02-23 /pmc/articles/PMC8864947/ /pubmed/35218789 http://dx.doi.org/10.1016/j.jinf.2022.02.023 Text en © 2022 The British Infection Association. Published by Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Letter to the Editor
Pascarella, Stefano
Ciccozzi, Massimo
Bianchi, Martina
Benvenuto, Domenico
Cauda, Roberto
Cassone, Antonio
The value of electrostatic potentials of the spike receptor binding and N-terminal domains in addressing transmissibility and infectivity of SARS-CoV-2 variants of concern
title The value of electrostatic potentials of the spike receptor binding and N-terminal domains in addressing transmissibility and infectivity of SARS-CoV-2 variants of concern
title_full The value of electrostatic potentials of the spike receptor binding and N-terminal domains in addressing transmissibility and infectivity of SARS-CoV-2 variants of concern
title_fullStr The value of electrostatic potentials of the spike receptor binding and N-terminal domains in addressing transmissibility and infectivity of SARS-CoV-2 variants of concern
title_full_unstemmed The value of electrostatic potentials of the spike receptor binding and N-terminal domains in addressing transmissibility and infectivity of SARS-CoV-2 variants of concern
title_short The value of electrostatic potentials of the spike receptor binding and N-terminal domains in addressing transmissibility and infectivity of SARS-CoV-2 variants of concern
title_sort value of electrostatic potentials of the spike receptor binding and n-terminal domains in addressing transmissibility and infectivity of sars-cov-2 variants of concern
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864947/
https://www.ncbi.nlm.nih.gov/pubmed/35218789
http://dx.doi.org/10.1016/j.jinf.2022.02.023
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