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In vitro activity of the orally bioavailable ceftibuten/VNRX-7145 (VNRX-5236 etzadroxil) combination against a challenge set of Enterobacterales pathogens carrying molecularly characterized β-lactamase genes

OBJECTIVES: This study assessed the activity of ceftibuten, ceftibuten combined with the active form (VNRX-5236) of the β-lactamase inhibitor VNRX-7145 and comparators against a challenge set of Gram-negative pathogens. METHODS: Two hundred and five Enterobacterales carrying plasmid AmpC (53 isolate...

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Detalles Bibliográficos
Autores principales:	Mendes, Rodrigo E, Rhomberg, Paul R, Watters, Amy A, Castanheira, Mariana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865001/ https://www.ncbi.nlm.nih.gov/pubmed/34849977 http://dx.doi.org/10.1093/jac/dkab425

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