Decrease of Intracellular Glutamine by STF-62247 Results in the Accumulation of Lipid Droplets in von Hippel-Lindau Deficient Cells

Kidney cancer is one of the top ten cancer diagnosed worldwide and its incidence has increased the last 20 years. Clear Cell Renal Cell Carcinoma (ccRCC) are characterized by mutations that inactivate the von Hippel-Lindau (VHL) tumor suppressor gene and evidence indicated alterations in metabolic p...

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Detalles Bibliográficos
Autores principales: Johnson, Mathieu, Nowlan, Sarah, Sahin, Gülsüm, Barnett, David A., Joy, Andrew P., Touaibia, Mohamed, Cuperlovic-Culf, Miroslava, Zofija Avizonis, Daina, Turcotte, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865074/
https://www.ncbi.nlm.nih.gov/pubmed/35223522
http://dx.doi.org/10.3389/fonc.2022.841054

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