MICA/B-targeted antibody promotes NK cell–driven tumor immunity in patients with intrahepatic cholangiocarcinoma

The major histocompatibility complex-class I chain related proteins A and B (MICA/B) is upregulated because of cellular stress and MICA/B shedding by cancer cells causes escape from NKG2D recognition favoring the emergence of cancers. Cholangiocarcinoma (CCA) is a relatively rare, though increasingl...

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Detalles Bibliográficos
Autores principales: Oliviero, Barbara, Varchetta, Stefania, Mele, Dalila, Pessino, Greta, Maiello, Roberta, Falleni, Monica, Tosi, Delfina, Donadon, Matteo, Soldani, Cristiana, Franceschini, Barbara, Torzilli, Guido, Piccolo, Gaetano, Barabino, Matteo, Opocher, Enrico, Maestri, Marcello, Bernuzzi, Stefano, Wucherpfennig, Kai W., Mondelli, Mario U., Mantovani, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865231/
https://www.ncbi.nlm.nih.gov/pubmed/35223192
http://dx.doi.org/10.1080/2162402X.2022.2035919

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