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Differentially methylated regions within lung cancer risk loci are enriched in deregulated enhancers

Genome-wide association studies (GWAS) have identified SNPs linked with lung cancer risk. Our aim was to discover the genes, non-coding RNAs, and regulatory elements within GWAS-identified risk regions that are deregulated in non-small cell lung carcinoma (NSCLC) to identify novel, clinically target...

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Detalles Bibliográficos
Autores principales: Laplana, Marina, Bieg, Matthias, Faltus, Christian, Melnik, Svitlana, Bogatyrova, Olga, Gu, Zuguang, Muley, Thomas, Meister, Michael, Dienemann, Hendrik, Herpel, Esther, Amos, Christopher I., Schlesner, Matthias, Eils, Roland, Plass, Christoph, Risch, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865272/
https://www.ncbi.nlm.nih.gov/pubmed/33595421
http://dx.doi.org/10.1080/15592294.2021.1878723