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Differentially methylated regions within lung cancer risk loci are enriched in deregulated enhancers
Genome-wide association studies (GWAS) have identified SNPs linked with lung cancer risk. Our aim was to discover the genes, non-coding RNAs, and regulatory elements within GWAS-identified risk regions that are deregulated in non-small cell lung carcinoma (NSCLC) to identify novel, clinically target...
Autores principales: | Laplana, Marina, Bieg, Matthias, Faltus, Christian, Melnik, Svitlana, Bogatyrova, Olga, Gu, Zuguang, Muley, Thomas, Meister, Michael, Dienemann, Hendrik, Herpel, Esther, Amos, Christopher I., Schlesner, Matthias, Eils, Roland, Plass, Christoph, Risch, Angela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865272/ https://www.ncbi.nlm.nih.gov/pubmed/33595421 http://dx.doi.org/10.1080/15592294.2021.1878723 |
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