Pro-mutagenic effects of the gut microbiota in a Lynch syndrome mouse model

The gut microbiota strongly impacts the development of sporadic colorectal cancer (CRC), but it is largely unknown how the microbiota affects the pathogenesis of mismatch-repair-deficient CRC in the context of Lynch syndrome. In a mouse model for Lynch syndrome, we found a nearly complete loss of in...

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Detalles Bibliográficos
Autores principales: Pieters, Wietske, Hugenholtz, Floor, Kos, Kevin, Cammeraat, Maxime, Moliej, Teddy C., Kaldenbach, Daphne, Klarenbeek, Sjoerd, Davids, Mark, Drost, Lisa, de Konink, Charlotte, Delzenne-Goette, Elly, de Visser, Karin E., te Riele, Hein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865281/
https://www.ncbi.nlm.nih.gov/pubmed/35188867
http://dx.doi.org/10.1080/19490976.2022.2035660

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865281/
https://www.ncbi.nlm.nih.gov/pubmed/35188867
http://dx.doi.org/10.1080/19490976.2022.2035660

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