Cargando…

Euvolemic off Pump Coronary Surgery Further Improves Early Postoperative Outcomes

BACKGROUND: Fluid resuscitation during Off-Pump Coronary Surgery (OPCABG) is still not protocolized and depends on multiple variables. We are exploring in this study whether a restrictive or euvolemic approach has any impact on short term surgical outcomes following OPCABG. METHODS: It is a retrospe...

Descripción completa

Detalles Bibliográficos
Autores principales: Rathore, Kaushalendra, Boon, Evan, Yussouf, Reza, Newman, Mark, Weightman, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865341/
https://www.ncbi.nlm.nih.gov/pubmed/35075015
http://dx.doi.org/10.4103/aca.ACA_139_20
_version_ 1784655619993632768
author Rathore, Kaushalendra
Boon, Evan
Yussouf, Reza
Newman, Mark
Weightman, William
author_facet Rathore, Kaushalendra
Boon, Evan
Yussouf, Reza
Newman, Mark
Weightman, William
author_sort Rathore, Kaushalendra
collection PubMed
description BACKGROUND: Fluid resuscitation during Off-Pump Coronary Surgery (OPCABG) is still not protocolized and depends on multiple variables. We are exploring in this study whether a restrictive or euvolemic approach has any impact on short term surgical outcomes following OPCABG. METHODS: It is a retrospective study of 300 patients analyzed based on the intraoperative fluid requirement with 150 patients in each group (Group I: Fluid <2 Litres, Group II: Fluid >2 Litres). RESULTS: Multivariable analysis showed echocardiography variables such as E/e ratio, LA volume index, and atrial fibrillation (AF). LA volume index is related to the higher fluid requirement. Group II had significantly higher ventilation time (P < 0.05), drain output (P = 0.05), drain removal time (<0.05), inotropic requirement, and diuretic use. CONCLUSION: The requirement of the intraoperative fluid was associated with various factors including diastolic dysfunction (left atrial volume index, left ventricle mass index, E/e ratio) and preoperative dual antiplatelet use. Group II patients had longer ventilation time, diuretics use, high drain output, and required drains for a longer period of time. Although there was no statistical difference among two groups as far as postoperative AF concerned, a reversal of AF to sinus rhythm was delayed in group II patients.
format Online
Article
Text
id pubmed-8865341
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Wolters Kluwer - Medknow
record_format MEDLINE/PubMed
spelling pubmed-88653412022-03-10 Euvolemic off Pump Coronary Surgery Further Improves Early Postoperative Outcomes Rathore, Kaushalendra Boon, Evan Yussouf, Reza Newman, Mark Weightman, William Ann Card Anaesth Original Article BACKGROUND: Fluid resuscitation during Off-Pump Coronary Surgery (OPCABG) is still not protocolized and depends on multiple variables. We are exploring in this study whether a restrictive or euvolemic approach has any impact on short term surgical outcomes following OPCABG. METHODS: It is a retrospective study of 300 patients analyzed based on the intraoperative fluid requirement with 150 patients in each group (Group I: Fluid <2 Litres, Group II: Fluid >2 Litres). RESULTS: Multivariable analysis showed echocardiography variables such as E/e ratio, LA volume index, and atrial fibrillation (AF). LA volume index is related to the higher fluid requirement. Group II had significantly higher ventilation time (P < 0.05), drain output (P = 0.05), drain removal time (<0.05), inotropic requirement, and diuretic use. CONCLUSION: The requirement of the intraoperative fluid was associated with various factors including diastolic dysfunction (left atrial volume index, left ventricle mass index, E/e ratio) and preoperative dual antiplatelet use. Group II patients had longer ventilation time, diuretics use, high drain output, and required drains for a longer period of time. Although there was no statistical difference among two groups as far as postoperative AF concerned, a reversal of AF to sinus rhythm was delayed in group II patients. Wolters Kluwer - Medknow 2022 2022-01-21 /pmc/articles/PMC8865341/ /pubmed/35075015 http://dx.doi.org/10.4103/aca.ACA_139_20 Text en Copyright: © 2022 Annals of Cardiac Anaesthesia https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Rathore, Kaushalendra
Boon, Evan
Yussouf, Reza
Newman, Mark
Weightman, William
Euvolemic off Pump Coronary Surgery Further Improves Early Postoperative Outcomes
title Euvolemic off Pump Coronary Surgery Further Improves Early Postoperative Outcomes
title_full Euvolemic off Pump Coronary Surgery Further Improves Early Postoperative Outcomes
title_fullStr Euvolemic off Pump Coronary Surgery Further Improves Early Postoperative Outcomes
title_full_unstemmed Euvolemic off Pump Coronary Surgery Further Improves Early Postoperative Outcomes
title_short Euvolemic off Pump Coronary Surgery Further Improves Early Postoperative Outcomes
title_sort euvolemic off pump coronary surgery further improves early postoperative outcomes
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865341/
https://www.ncbi.nlm.nih.gov/pubmed/35075015
http://dx.doi.org/10.4103/aca.ACA_139_20
work_keys_str_mv AT rathorekaushalendra euvolemicoffpumpcoronarysurgeryfurtherimprovesearlypostoperativeoutcomes
AT boonevan euvolemicoffpumpcoronarysurgeryfurtherimprovesearlypostoperativeoutcomes
AT yussoufreza euvolemicoffpumpcoronarysurgeryfurtherimprovesearlypostoperativeoutcomes
AT newmanmark euvolemicoffpumpcoronarysurgeryfurtherimprovesearlypostoperativeoutcomes
AT weightmanwilliam euvolemicoffpumpcoronarysurgeryfurtherimprovesearlypostoperativeoutcomes