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Hippocampus-Based Mitochondrial Respiratory Function Decline Is Responsible for Perioperative Neurocognitive Disorders

Perioperative neurocognitive disorders (PNDs) are a type of cognitive dysfunction occurring with a higher incidence in elderly patients. However, the pathological mechanism of PND and effective treatment remain elusive. We generated a PND mouse model by providing wild-type mice with surgical trauma;...

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Detalles Bibliográficos
Autores principales: He, Keqiang, Zhang, Juan, Zhang, Wei, Wang, Sheng, Li, Dingfeng, Ma, Xiaolin, Wu, Xiaofan, Chai, Xiaoqing, Liu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865419/
https://www.ncbi.nlm.nih.gov/pubmed/35221986
http://dx.doi.org/10.3389/fnagi.2022.772066