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Endogenous CRISPR-Cas Systems in Group I Clostridium botulinum and Clostridium sporogenes Do Not Directly Target the Botulinum Neurotoxin Gene Cluster

Most strains of proteolytic group I Clostridium botulinum (G1 C. botulinum) and some strains of Clostridium sporogenes possess genes encoding botulinum neurotoxin (BoNT), a potent neuroparalytic agent. Within G1 C. botulinum, conserved bont gene clusters of three major toxin serotypes (bont/A/B/F) c...

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Detalles Bibliográficos
Autores principales:	Wentz, Travis G., Tremblay, Benjamin J. M., Bradshaw, Marite, Doxey, Andrew C., Sharma, Shashi K., Sauer, John-Demian, Pellett, Sabine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865420/ https://www.ncbi.nlm.nih.gov/pubmed/35222299 http://dx.doi.org/10.3389/fmicb.2021.787726

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