Detecting molecular subtypes from multi-omics datasets using SUMO

We present a data integration framework that uses non-negative matrix factorization of patient-similarity networks to integrate continuous multi-omics datasets for molecular subtyping. It is demonstrated to have the capability to handle missing data without using imputation and to be consistently am...

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Detalles Bibliográficos
Autores principales: Sienkiewicz, Karolina, Chen, Jinyu, Chatrath, Ajay, Lawson, John T., Sheffield, Nathan C., Zhang, Louxin, Ratan, Aakrosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865426/
https://www.ncbi.nlm.nih.gov/pubmed/35211690
http://dx.doi.org/10.1016/j.crmeth.2021.100152

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