A Hybrid Soluble gp130/Spike-Nanobody Fusion Protein Simultaneously Blocks Interleukin-6 trans-Signaling and Cellular Infection with SARS-CoV-2

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can induce mild to life-threatening symptoms. Especially individuals over 60 years of age or with underlying comorbidities, including heart or lung disease and diabetes, or immunocompromised patients are at a higher risk. Fatal m...

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Detalles Bibliográficos
Autores principales: Ettich, Julia, Werner, Julia, Weitz, Hendrik T., Mueller, Eva, Schwarzer, Roland, Lang, Philipp A., Scheller, Jürgen, Moll, Jens M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Cellular Response to Infection
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865451/
https://www.ncbi.nlm.nih.gov/pubmed/34935434
http://dx.doi.org/10.1128/jvi.01622-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865451/
https://www.ncbi.nlm.nih.gov/pubmed/34935434
http://dx.doi.org/10.1128/jvi.01622-21

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