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Microglia Do Not Restrict SARS-CoV-2 Replication following Infection of the Central Nervous System of K18-Human ACE2 Transgenic Mice
Unlike SARS-CoV-1 and MERS-CoV, infection with SARS-CoV-2, the viral pathogen responsible for COVID-19, is often associated with neurologic symptoms that range from mild to severe, yet increasing evidence argues the virus does not exhibit extensive neuroinvasive properties. We demonstrate SARS-CoV-2...
Autores principales: | Olivarria, Gema M., Cheng, Yuting, Furman, Susana, Pachow, Collin, Hohsfield, Lindsay A., Smith-Geater, Charlene, Miramontes, Ricardo, Wu, Jie, Burns, Mara S., Tsourmas, Kate I., Stocksdale, Jennifer, Manlapaz, Cynthia, Yong, William H., Teijaro, John, Edwards, Robert, Green, Kim N., Thompson, Leslie M., Lane, Thomas E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865461/ https://www.ncbi.nlm.nih.gov/pubmed/34935438 http://dx.doi.org/10.1128/jvi.01969-21 |
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