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RFX transcription factors control a miR-150/PDAP1 axis that restrains the proliferation of human T cells

Within the immune system, microRNAs (miRNAs) exert key regulatory functions. However, what are the mRNA targets regulated by miRNAs and how miRNAs are transcriptionally regulated themselves remain for the most part unknown. We found that in primary human memory T helper lymphocytes, miR-150 was the...

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Detalles Bibliográficos
Autores principales:	Chirichella, Michele, Bianchi, Niccolò, Džafo, Emina, Foli, Elena, Gualdrini, Francesco, Kenyon, Amy, Natoli, Gioacchino, Monticelli, Silvia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865640/ https://www.ncbi.nlm.nih.gov/pubmed/35143476 http://dx.doi.org/10.1371/journal.pbio.3001538

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