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A protease-activatable luminescent biosensor and reporter cell line for authentic SARS-CoV-2 infection

Efforts to define serological correlates of protection against COVID-19 have been hampered by the lack of a simple, scalable, standardised assay for SARS-CoV-2 infection and antibody neutralisation. Plaque assays remain the gold standard, but are impractical for high-throughput screening. In this st...

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Detalles Bibliográficos
Autores principales: Gerber, Pehuén Pereyra, Duncan, Lidia M., Greenwood, Edward JD, Marelli, Sara, Naamati, Adi, Teixeira-Silva, Ana, Crozier, Thomas WM, Gabaev, Ildar, Zhan, Jun R., Mulroney, Thomas E., Horner, Emily C., Doffinger, Rainer, Willis, Anne E., Thaventhiran, James ED, Protasio, Anna V., Matheson, Nicholas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865646/
https://www.ncbi.nlm.nih.gov/pubmed/35143592
http://dx.doi.org/10.1371/journal.ppat.1010265

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