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Cooperativity of catalytic and lectin-like domain of Trypanosoma congolense trans-sialidase modulates its catalytic activity

Trans-sialidases (TS) represent a multi-gene family of unusual enzymes, which catalyse the transfer of terminal sialic acids (Sia) from sialoglycoconjugates to terminal galactose or N-acetylgalactosamine residues of oligosaccharides without the requirement of CMP-Neu5Ac, the activated Sia used by ty...

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Detalles Bibliográficos
Autores principales:	Waespy, Mario, Gbem, Thaddeus Termulun, Dinesh Kumar, Nilima, Solaiyappan Mani, Shanmugam, Rosenau, Jana, Dietz, Frank, Kelm, Sørge
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865650/ https://www.ncbi.nlm.nih.gov/pubmed/35130274 http://dx.doi.org/10.1371/journal.pntd.0009585

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