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Scaling-up the delivery of dog vaccination campaigns against rabies in Tanzania

An increasing number of countries are committing to meet the global target to eliminate human deaths from dog-mediated rabies by 2030. Mass dog vaccination is central to this strategy. To interrupt rabies transmission from dogs to humans, the World Health Organization recommends that vaccination cam...

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Autores principales: Sambo, Maganga, Ferguson, Elaine A., Abela-Ridder, Bernadette, Changalucha, Joel, Cleaveland, Sarah, Lushasi, Kennedy, Mchau, Geofrey Joseph, Nanai, Alphoncina, Nonga, Hezron, Steenson, Rachel, Johnson, Paul CD, Hampson, Katie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865671/
https://www.ncbi.nlm.nih.gov/pubmed/35143490
http://dx.doi.org/10.1371/journal.pntd.0010124
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author Sambo, Maganga
Ferguson, Elaine A.
Abela-Ridder, Bernadette
Changalucha, Joel
Cleaveland, Sarah
Lushasi, Kennedy
Mchau, Geofrey Joseph
Nanai, Alphoncina
Nonga, Hezron
Steenson, Rachel
Johnson, Paul CD
Hampson, Katie
author_facet Sambo, Maganga
Ferguson, Elaine A.
Abela-Ridder, Bernadette
Changalucha, Joel
Cleaveland, Sarah
Lushasi, Kennedy
Mchau, Geofrey Joseph
Nanai, Alphoncina
Nonga, Hezron
Steenson, Rachel
Johnson, Paul CD
Hampson, Katie
author_sort Sambo, Maganga
collection PubMed
description An increasing number of countries are committing to meet the global target to eliminate human deaths from dog-mediated rabies by 2030. Mass dog vaccination is central to this strategy. To interrupt rabies transmission from dogs to humans, the World Health Organization recommends that vaccination campaigns should be carried out every year in all dog-owning communities vaccinating 70% of their susceptible dogs. Monitoring and evaluation of dog vaccination campaigns are needed to measure progress towards elimination. In this study, we measured the delivery performance of large-scale vaccination campaigns implemented in 25 districts in south-east Tanzania from 2010 until 2017. We used regression modelling to infer the factors associated with, and potentially influencing the successful delivery of vaccination campaigns. During 2010–2017, five rounds of vaccination campaigns were carried out, vaccinating in total 349,513 dogs in 2,066 administrative vaccination units (rural villages or urban wards). Progressively more dogs were vaccinated over the successive campaigns. The campaigns did not reach all vaccination units each year, with only 16–28% of districts achieving 100% campaign completeness (where all units were vaccinated). During 2013–2017 when vaccination coverage was monitored, approximately 20% of vaccination units achieved the recommended 70% coverage, with average coverage around 50%. Campaigns were also not completed at annual intervals, with the longest interval between campaigns being 27 months. Our analysis revealed that districts with higher budgets generally achieved higher completeness, with a twofold difference in district budget increasing the odds of a vaccination unit being reached by a campaign by slightly more than twofold (OR: 2.29; 95% CI: 1.69–3.09). However, higher budgets did not necessarily result in higher coverage within vaccination units that were reached. We recommend national programs regularly monitor and evaluate the performance of their vaccination campaigns, so as to identify factors hindering their effective delivery and to guide remedial action.
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spelling pubmed-88656712022-02-24 Scaling-up the delivery of dog vaccination campaigns against rabies in Tanzania Sambo, Maganga Ferguson, Elaine A. Abela-Ridder, Bernadette Changalucha, Joel Cleaveland, Sarah Lushasi, Kennedy Mchau, Geofrey Joseph Nanai, Alphoncina Nonga, Hezron Steenson, Rachel Johnson, Paul CD Hampson, Katie PLoS Negl Trop Dis Research Article An increasing number of countries are committing to meet the global target to eliminate human deaths from dog-mediated rabies by 2030. Mass dog vaccination is central to this strategy. To interrupt rabies transmission from dogs to humans, the World Health Organization recommends that vaccination campaigns should be carried out every year in all dog-owning communities vaccinating 70% of their susceptible dogs. Monitoring and evaluation of dog vaccination campaigns are needed to measure progress towards elimination. In this study, we measured the delivery performance of large-scale vaccination campaigns implemented in 25 districts in south-east Tanzania from 2010 until 2017. We used regression modelling to infer the factors associated with, and potentially influencing the successful delivery of vaccination campaigns. During 2010–2017, five rounds of vaccination campaigns were carried out, vaccinating in total 349,513 dogs in 2,066 administrative vaccination units (rural villages or urban wards). Progressively more dogs were vaccinated over the successive campaigns. The campaigns did not reach all vaccination units each year, with only 16–28% of districts achieving 100% campaign completeness (where all units were vaccinated). During 2013–2017 when vaccination coverage was monitored, approximately 20% of vaccination units achieved the recommended 70% coverage, with average coverage around 50%. Campaigns were also not completed at annual intervals, with the longest interval between campaigns being 27 months. Our analysis revealed that districts with higher budgets generally achieved higher completeness, with a twofold difference in district budget increasing the odds of a vaccination unit being reached by a campaign by slightly more than twofold (OR: 2.29; 95% CI: 1.69–3.09). However, higher budgets did not necessarily result in higher coverage within vaccination units that were reached. We recommend national programs regularly monitor and evaluate the performance of their vaccination campaigns, so as to identify factors hindering their effective delivery and to guide remedial action. Public Library of Science 2022-02-10 /pmc/articles/PMC8865671/ /pubmed/35143490 http://dx.doi.org/10.1371/journal.pntd.0010124 Text en © 2022 Sambo et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Sambo, Maganga
Ferguson, Elaine A.
Abela-Ridder, Bernadette
Changalucha, Joel
Cleaveland, Sarah
Lushasi, Kennedy
Mchau, Geofrey Joseph
Nanai, Alphoncina
Nonga, Hezron
Steenson, Rachel
Johnson, Paul CD
Hampson, Katie
Scaling-up the delivery of dog vaccination campaigns against rabies in Tanzania
title Scaling-up the delivery of dog vaccination campaigns against rabies in Tanzania
title_full Scaling-up the delivery of dog vaccination campaigns against rabies in Tanzania
title_fullStr Scaling-up the delivery of dog vaccination campaigns against rabies in Tanzania
title_full_unstemmed Scaling-up the delivery of dog vaccination campaigns against rabies in Tanzania
title_short Scaling-up the delivery of dog vaccination campaigns against rabies in Tanzania
title_sort scaling-up the delivery of dog vaccination campaigns against rabies in tanzania
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865671/
https://www.ncbi.nlm.nih.gov/pubmed/35143490
http://dx.doi.org/10.1371/journal.pntd.0010124
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