Cargando…

Combining explainable machine learning, demographic and multi-omic data to inform precision medicine strategies for inflammatory bowel disease

Inflammatory bowel diseases (IBDs), including ulcerative colitis and Crohn’s disease, affect several million individuals worldwide. These diseases are heterogeneous at the clinical, immunological and genetic levels and result from complex host and environmental interactions. Investigating drug effic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gardiner, Laura-Jayne, Carrieri, Anna Paola, Bingham, Karen, Macluskie, Graeme, Bunton, David, McNeil, Marian, Pyzer-Knapp, Edward O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865677/ https://www.ncbi.nlm.nih.gov/pubmed/35196350 http://dx.doi.org/10.1371/journal.pone.0263248

Ejemplares similares

Using human in vitro transcriptome analysis to build trustworthy machine learning models for prediction of animal drug toxicity
por: Gardiner, Laura-Jayne, et al.
Publicado: (2020)

Interpreting machine learning models to investigate circadian regulation and facilitate exploration of clock function
por: Gardiner, Laura-Jayne, et al.
Publicado: (2021)

Application of pharmacogenomics and bioinformatics to exemplify the utility of human ex vivo organoculture models in the field of precision medicine
por: Cowan, Karen, et al.
Publicado: (2019)

Machine learning in chemistry
por: Pyzer-Knapp, Edward O, et al.
Publicado: (2019)

Explainable AI reveals changes in skin microbiome composition linked to phenotypic differences
por: Carrieri, Anna Paola, et al.
Publicado: (2021)

Deep learning for physical scientists: accelerating research with machine learning
por: Pyzer-Knapp, Edward O
Publicado: (2019)

Machine learning exciton dynamics
por: Häse, Florian, et al.
Publicado: (2016)

Scalable in-memory processing of omics workflows
por: Elisseev, Vadim, et al.
Publicado: (2022)

The MultiOmics Explainer: explaining omics results in the context of a pathway/genome database
por: Paley, Suzanne, et al.
Publicado: (2019)

Explainable machine learning for precise fatigue crack tip detection
por: Melching, David, et al.
Publicado: (2022)

An optimized intermolecular force field for hydrogen-bonded organic molecular crystals using atomic multipole electrostatics
por: Pyzer-Knapp, Edward O., et al.
Publicado: (2016)

Advancing the precision management of inflammatory bowel disease in the era of omics approaches and new technology
por: Liu, Xin-Yu, et al.
Publicado: (2023)

Accelerating computational discovery of porous solids through improved navigation of energy-structure-function maps
por: Pyzer-Knapp, Edward O., et al.
Publicado: (2021)

Editorial: Machine Learning Advanced Dynamic Omics Data Analysis for Precision Medicine
por: Zeng, Tao, et al.
Publicado: (2020)

Explaining the Neolithic Demographic Transition
por: Bocquet-Appel, Jean-Pierre
Publicado: (2008)

Explaining evolution via constrained persistent perfect phylogeny
por: Bonizzoni, Paola, et al.
Publicado: (2014)

Precision oncology: a review to assess interpretability in several explainable methods
por: Gimeno, Marian, et al.
Publicado: (2023)

Explainable artificial intelligence for precision medicine in acute myeloid leukemia
por: Gimeno, Marian, et al.
Publicado: (2022)

Streaming histogram sketching for rapid microbiome analytics
por: Rowe, Will PM, et al.
Publicado: (2019)

Multi-omics approaches for precision obesity management: Potentials and limitations of omics in precision prevention, treatment and risk reduction of obesity
por: Woldemariam, Selam, et al.
Publicado: (2023)

Cross-Platform Omics Prediction procedure: a statistical machine learning framework for wider implementation of precision medicine
por: Wang, Kevin Y. X., et al.
Publicado: (2022)

Multi-omics disease module detection with an explainable Greedy Decision Forest
por: Pfeifer, Bastian, et al.
Publicado: (2022)

Are We Ready to Use the Omics Strategies for Precision Medicine?
por: Kim, Jayoung
Publicado: (2016)

The Need for Multi-Omics Biomarker Signatures in Precision Medicine
por: Olivier, Michael, et al.
Publicado: (2019)

Editorial: Multi-omics studies and applications in precision medicine
por: Everad John, Arivusudar
Publicado: (2022)

Towards precision medicine: Omics approach for COVID-19
por: Cen, Xiaoping, et al.
Publicado: (2023)

Precision machines
por: Jiang, Zhuangde, et al.
Publicado: (2020)

Omics and Machine Learning in Transfusion Medicine
por: D’Alessandro, Angelo, et al.
Publicado: (2023)

Application of single-cell omics in inflammatory bowel disease
por: Zheng, Hengqi Betty
Publicado: (2023)

Machine Learning Modeling from Omics Data as Prospective Tool for Improvement of Inflammatory Bowel Disease Diagnosis and Clinical Classifications
por: Stankovic, Biljana, et al.
Publicado: (2021)

Towards precision medicine: The application of omics technologies in asthma management
por: Scelfo, Chiara, et al.
Publicado: (2018)

Precision Medicine in Childhood Asthma: Omic Studies of Treatment Response
por: Perez-Garcia, Javier, et al.
Publicado: (2020)

Multi-omics approach to precision medicine for immune-mediated diseases
por: Ota, Mineto, et al.
Publicado: (2021)

Holistic Integration of Omics Tools for Precision Nutrition in Health and Disease
por: Ramos-Lopez, Omar, et al.
Publicado: (2022)

Precision periodontal care: from omics discoveries to chairside diagnostics
por: Bostanci, Nagihan, et al.
Publicado: (2023)

Explainable Machine Learning for Breakdown Prediction in High Gradient RF Cavities
por: Obermair, Christoph, et al.
Publicado: (2022)

Principles and Practice of Explainable Machine Learning
por: Belle, Vaishak, et al.
Publicado: (2021)

Explainable machine learning for diffraction patterns
por: Nawaz, Shah, et al.
Publicado: (2023)

Relative demographic susceptibility does not explain the extinction chronology of Sahul’s megafauna
por: Bradshaw, Corey JA, et al.
Publicado: (2021)

Demographic and life history traits explain patterns in species vulnerability to extinction
por: Hernández-Yáñez, Haydée, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_0ddd02ummjoq9dna5mfhlkd42i