Longitudinal single-cell RNA-seq analysis reveals stress-promoted chemoresistance in metastatic ovarian cancer

Chemotherapy resistance is a critical contributor to cancer mortality and thus an urgent unmet challenge in oncology. To characterize chemotherapy resistance processes in high-grade serous ovarian cancer, we prospectively collected tissue samples before and after chemotherapy and analyzed their tran...

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Detalles Bibliográficos
Autores principales: Zhang, Kaiyang, Erkan, Erdogan Pekcan, Jamalzadeh, Sanaz, Dai, Jun, Andersson, Noora, Kaipio, Katja, Lamminen, Tarja, Mansuri, Naziha, Huhtinen, Kaisa, Carpén, Olli, Hietanen, Sakari, Oikkonen, Jaana, Hynninen, Johanna, Virtanen, Anni, Häkkinen, Antti, Hautaniemi, Sampsa, Vähärautio, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865800/
https://www.ncbi.nlm.nih.gov/pubmed/35196078
http://dx.doi.org/10.1126/sciadv.abm1831

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