CASPorter: A Novel Inducible Human CASP1/NALP3/ASC Inflammasome Biosensor

BACKGROUND: Following our 2015 elucidation of the CASP1/NALP3 inflammasome mechanism of glucocorticoid (GC)-resistance in pediatric acute lymphoblastic leukemia (ALL) patients, we engineered a cell-based CASP1/NALP3 reporter system suitable for high-throughput screening (HTS) of small molecule libra...

Descripción completa

Detalles Bibliográficos
Autores principales: Zou, Chan, Beard, Jordan A, Yang, Guoping, Evans, William E, Bonten, Erik J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865862/
https://www.ncbi.nlm.nih.gov/pubmed/35221708
http://dx.doi.org/10.2147/JIR.S333725

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865862/
https://www.ncbi.nlm.nih.gov/pubmed/35221708
http://dx.doi.org/10.2147/JIR.S333725

Ejemplares similares