Vaccine-Induced, High-Magnitude HIV Env-Specific Antibodies with Fc-Mediated Effector Functions Are Insufficient to Protect Infant Rhesus Macaques against Oral SHIV Infection

Improved access to antiretroviral therapy (ART) and antenatal care has significantly reduced in utero and peripartum mother-to-child human immunodeficiency virus (HIV) transmission. However, as breast milk transmission of HIV still occurs at an unacceptable rate, there remains a need to develop an e...

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Detalles Bibliográficos
Autores principales: Curtis, Alan D., Saha, Pooja T., Dennis, Maria, Berendam, Stella J., Ramasubramanian, Pratamesh, Cross, Kaitlyn A., Alam, S. Munir, Ferrari, Guido, Kozlowski, Pamela A., Fouda, Genevieve G., Hudgens, Michael G., Van Rompay, Koen K. A., Pollara, Justin, Permar, Sallie R., De Paris, Kristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865927/
https://www.ncbi.nlm.nih.gov/pubmed/35196125
http://dx.doi.org/10.1128/msphere.00839-21

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