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Effects of malnutrition on mortality in oldest-old inpatients with COVID-19 in the GERIA-COVID cohort

We assessed the impact of malnutrition on 14-day, 28-day, and 3-month mortality risk in oldest-old inpatients aged ≥80 years with COVID-19 in the hospital-based GERIA-COVID cohort. Malnutrition was assessed on hospital admission using the Geriatric Nutritional Risk Index (GNRI). Potential confounder...

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Autores principales: Sanchez-Rodriguez, Dolores, Sacco, Guillaume, Gautier, Jennifer, Brière, Olivier, Annweiler, Cédric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865952/
https://www.ncbi.nlm.nih.gov/pubmed/35688493
http://dx.doi.org/10.1016/j.maturitas.2021.11.016
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author Sanchez-Rodriguez, Dolores
Sacco, Guillaume
Gautier, Jennifer
Brière, Olivier
Annweiler, Cédric
author_facet Sanchez-Rodriguez, Dolores
Sacco, Guillaume
Gautier, Jennifer
Brière, Olivier
Annweiler, Cédric
author_sort Sanchez-Rodriguez, Dolores
collection PubMed
description We assessed the impact of malnutrition on 14-day, 28-day, and 3-month mortality risk in oldest-old inpatients aged ≥80 years with COVID-19 in the hospital-based GERIA-COVID cohort. Malnutrition was assessed on hospital admission using the Geriatric Nutritional Risk Index (GNRI). Potential confounders were age, sex, functional abilities, number of acute health issues, CRP level, hypertension, cardiomyopathy, malignancies, use of antibiotics, and respiratory treatments. Seventy-eight participants (88.9 ± 4.3 years old, 55% women) were included. Of these, 82.1% had survived at day 14, 78.2% at day 28, and 70.5% after 3 months. No association between malnutrition according to the GNRI and 14-day (P = 0.324), 28-day (P = 0.166), or 3-month mortality (P = 0.109) was found. Thus, malnutrition according to the GNRI was not associated with mortality within the first 3 months of diagnosis of COVID-19 among oldest-old inpatients.
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spelling pubmed-88659522022-02-24 Effects of malnutrition on mortality in oldest-old inpatients with COVID-19 in the GERIA-COVID cohort Sanchez-Rodriguez, Dolores Sacco, Guillaume Gautier, Jennifer Brière, Olivier Annweiler, Cédric Maturitas Article We assessed the impact of malnutrition on 14-day, 28-day, and 3-month mortality risk in oldest-old inpatients aged ≥80 years with COVID-19 in the hospital-based GERIA-COVID cohort. Malnutrition was assessed on hospital admission using the Geriatric Nutritional Risk Index (GNRI). Potential confounders were age, sex, functional abilities, number of acute health issues, CRP level, hypertension, cardiomyopathy, malignancies, use of antibiotics, and respiratory treatments. Seventy-eight participants (88.9 ± 4.3 years old, 55% women) were included. Of these, 82.1% had survived at day 14, 78.2% at day 28, and 70.5% after 3 months. No association between malnutrition according to the GNRI and 14-day (P = 0.324), 28-day (P = 0.166), or 3-month mortality (P = 0.109) was found. Thus, malnutrition according to the GNRI was not associated with mortality within the first 3 months of diagnosis of COVID-19 among oldest-old inpatients. Elsevier B.V. 2022-07 2022-02-24 /pmc/articles/PMC8865952/ /pubmed/35688493 http://dx.doi.org/10.1016/j.maturitas.2021.11.016 Text en © 2022 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Sanchez-Rodriguez, Dolores
Sacco, Guillaume
Gautier, Jennifer
Brière, Olivier
Annweiler, Cédric
Effects of malnutrition on mortality in oldest-old inpatients with COVID-19 in the GERIA-COVID cohort
title Effects of malnutrition on mortality in oldest-old inpatients with COVID-19 in the GERIA-COVID cohort
title_full Effects of malnutrition on mortality in oldest-old inpatients with COVID-19 in the GERIA-COVID cohort
title_fullStr Effects of malnutrition on mortality in oldest-old inpatients with COVID-19 in the GERIA-COVID cohort
title_full_unstemmed Effects of malnutrition on mortality in oldest-old inpatients with COVID-19 in the GERIA-COVID cohort
title_short Effects of malnutrition on mortality in oldest-old inpatients with COVID-19 in the GERIA-COVID cohort
title_sort effects of malnutrition on mortality in oldest-old inpatients with covid-19 in the geria-covid cohort
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865952/
https://www.ncbi.nlm.nih.gov/pubmed/35688493
http://dx.doi.org/10.1016/j.maturitas.2021.11.016
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