Cargando…

An Insight Into Flatbush Diabetes: A Rare Form of Diabetes

Ketone-prone diabetes or Flatbush diabetes is being increasingly recognized worldwide. It is typically seen in obese middle-aged men with a family history of Type 2 DM. Atypicality in the onset of age and gender variation is increasingly observed worldwide. Predisposition to glucose desensitization...

Descripción completa

Detalles Bibliográficos
Autores principales: Shankar, Malavika, Chowdhury, Tutul, Gousy, Nicole, Parthasarathi, Ashwaghosha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865986/
https://www.ncbi.nlm.nih.gov/pubmed/35228926
http://dx.doi.org/10.7759/cureus.21567
_version_ 1784655737681608704
author Shankar, Malavika
Chowdhury, Tutul
Gousy, Nicole
Parthasarathi, Ashwaghosha
author_facet Shankar, Malavika
Chowdhury, Tutul
Gousy, Nicole
Parthasarathi, Ashwaghosha
author_sort Shankar, Malavika
collection PubMed
description Ketone-prone diabetes or Flatbush diabetes is being increasingly recognized worldwide. It is typically seen in obese middle-aged men with a family history of Type 2 DM. Atypicality in the onset of age and gender variation is increasingly observed worldwide. Predisposition to glucose desensitization is one of many unclear pathophysiologic mechanisms which is why extensive studies are obligatory. After intensive insulin therapy, many patients eventually become insulin-independent and attain euglycemia with oral hypoglycemic agents or with diet alone due to the recovered functionality of pancreatic beta cells. Our report sheds light on the atypicality of presentation and summarizes the main diagnostic features of this rare form of diabetes. Increased awareness of this entity can facilitate early diagnosis and management.
format Online
Article
Text
id pubmed-8865986
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-88659862022-02-27 An Insight Into Flatbush Diabetes: A Rare Form of Diabetes Shankar, Malavika Chowdhury, Tutul Gousy, Nicole Parthasarathi, Ashwaghosha Cureus Endocrinology/Diabetes/Metabolism Ketone-prone diabetes or Flatbush diabetes is being increasingly recognized worldwide. It is typically seen in obese middle-aged men with a family history of Type 2 DM. Atypicality in the onset of age and gender variation is increasingly observed worldwide. Predisposition to glucose desensitization is one of many unclear pathophysiologic mechanisms which is why extensive studies are obligatory. After intensive insulin therapy, many patients eventually become insulin-independent and attain euglycemia with oral hypoglycemic agents or with diet alone due to the recovered functionality of pancreatic beta cells. Our report sheds light on the atypicality of presentation and summarizes the main diagnostic features of this rare form of diabetes. Increased awareness of this entity can facilitate early diagnosis and management. Cureus 2022-01-24 /pmc/articles/PMC8865986/ /pubmed/35228926 http://dx.doi.org/10.7759/cureus.21567 Text en Copyright © 2022, Shankar et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Endocrinology/Diabetes/Metabolism
Shankar, Malavika
Chowdhury, Tutul
Gousy, Nicole
Parthasarathi, Ashwaghosha
An Insight Into Flatbush Diabetes: A Rare Form of Diabetes
title An Insight Into Flatbush Diabetes: A Rare Form of Diabetes
title_full An Insight Into Flatbush Diabetes: A Rare Form of Diabetes
title_fullStr An Insight Into Flatbush Diabetes: A Rare Form of Diabetes
title_full_unstemmed An Insight Into Flatbush Diabetes: A Rare Form of Diabetes
title_short An Insight Into Flatbush Diabetes: A Rare Form of Diabetes
title_sort insight into flatbush diabetes: a rare form of diabetes
topic Endocrinology/Diabetes/Metabolism
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865986/
https://www.ncbi.nlm.nih.gov/pubmed/35228926
http://dx.doi.org/10.7759/cureus.21567
work_keys_str_mv AT shankarmalavika aninsightintoflatbushdiabetesarareformofdiabetes
AT chowdhurytutul aninsightintoflatbushdiabetesarareformofdiabetes
AT gousynicole aninsightintoflatbushdiabetesarareformofdiabetes
AT parthasarathiashwaghosha aninsightintoflatbushdiabetesarareformofdiabetes
AT shankarmalavika insightintoflatbushdiabetesarareformofdiabetes
AT chowdhurytutul insightintoflatbushdiabetesarareformofdiabetes
AT gousynicole insightintoflatbushdiabetesarareformofdiabetes
AT parthasarathiashwaghosha insightintoflatbushdiabetesarareformofdiabetes