Inorganic nitrate and nitrite ameliorate kidney fibrosis by restoring lipid metabolism via dual regulation of AMP-activated protein kinase and the AKT-PGC1α pathway

BACKGROUND: Renal fibrosis, associated with oxidative stress and nitric oxide (NO) deficiency, contributes to the development of chronic kidney disease and renal failure. As major energy source in maintaining renal physiological functions, tubular epithelial cells with decreased fatty acid oxidation...

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Detalles Bibliográficos
Autores principales: Li, Xuechen, Zhuge, Zhengbing, Carvalho, Lucas Rannier R.A., Braga, Valdir A., Lucena, Ricardo Barbosa, Li, Shuijie, Schiffer, Tomas A., Han, Huirong, Weitzberg, Eddie, Lundberg, Jon O., Carlström, Mattias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866060/
https://www.ncbi.nlm.nih.gov/pubmed/35217293
http://dx.doi.org/10.1016/j.redox.2022.102266

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866060/
https://www.ncbi.nlm.nih.gov/pubmed/35217293
http://dx.doi.org/10.1016/j.redox.2022.102266

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