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Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies
The SARS-CoV-2 B.1.1.529 (Omicron) variant contains 15 mutations of the receptor-binding domain (RBD). How Omicron evades RBD-targeted neutralizing antibodies requires immediate investigation. Here we use high-throughput yeast display screening(1,2) to determine the profiles of RBD escaping mutation...
Autores principales: | Cao, Yunlong, Wang, Jing, Jian, Fanchong, Xiao, Tianhe, Song, Weiliang, Yisimayi, Ayijiang, Huang, Weijin, Li, Qianqian, Wang, Peng, An, Ran, Wang, Yao, Niu, Xiao, Yang, Sijie, Liang, Hui, Sun, Haiyan, Li, Tao, Yu, Yuanling, Cui, Qianqian, Liu, Shuo, Yang, Xiaodong, Du, Shuo, Zhang, Zhiying, Hao, Xiaohua, Shao, Fei, Jin, Ronghua, Wang, Xiangxi, Xiao, Junyu, Wang, Youchun, Xie, Xiaoliang Sunney |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866119/ https://www.ncbi.nlm.nih.gov/pubmed/35016194 http://dx.doi.org/10.1038/s41586-021-04385-3 |
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