Intestinal microbe-dependent ω3 lipid metabolite αKetoA prevents inflammatory diseases in mice and cynomolgus macaques

Dietary ω3 fatty acids have important health benefits and exert their potent bioactivity through conversion to lipid mediators. Here, we demonstrate that microbiota play an essential role in the body’s use of dietary lipids for the control of inflammatory diseases. We found that amounts of 10-hydrox...

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Detalles Bibliográficos
Autores principales: Nagatake, Takahiro, Kishino, Shigenobu, Urano, Emiko, Murakami, Haruka, Kitamura, Nahoko, Konishi, Kana, Ohno, Harumi, Tiwari, Prabha, Morimoto, Sakiko, Node, Eri, Adachi, Jun, Abe, Yuichi, Isoyama, Junko, Sawane, Kento, Honda, Tetsuya, Inoue, Asuka, Uwamizu, Akiharu, Matsuzaka, Takashi, Miyamoto, Yoichi, Hirata, So-ichiro, Saika, Azusa, Shibata, Yuki, Hosomi, Koji, Matsunaga, Ayu, Shimano, Hitoshi, Arita, Makoto, Aoki, Junken, Oka, Masahiro, Matsutani, Akira, Tomonaga, Takeshi, Kabashima, Kenji, Miyachi, Motohiko, Yasutomi, Yasuhiro, Ogawa, Jun, Kunisawa, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866125/
https://www.ncbi.nlm.nih.gov/pubmed/35013573
http://dx.doi.org/10.1038/s41385-021-00477-5

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