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Immunomodulatory potential of in vivo natural killer T (NKT) activation by NKTT320 in Mauritian-origin cynomolgus macaques

Invariant natural killer T-lymphocytes (iNKT) are unique immunomodulatory innate T cells with an invariant TCRα recognizing glycolipids presented on MHC class-I-like CD1d molecules. Activated iNKT rapidly secrete pro-and anti-inflammatory cytokines, potentiate immunity, and modulate inflammation. He...

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Detalles Bibliográficos
Autores principales:	Bond, Nell G., Fahlberg, Marissa D., Yu, Shan, Rout, Namita, Tran, Dollnovan, Fitzpatrick-Schmidt, Taylor, Sprehe, Lesli M., Scheef, Elizabeth A., Mudd, Joseph C., Schaub, Robert, Kaur, Amitinder
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866157/ https://www.ncbi.nlm.nih.gov/pubmed/35243248 http://dx.doi.org/10.1016/j.isci.2022.103889

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