Cargando…

A DNA-Methylation-Driven Genes Based Prognostic Signature Reveals Immune Microenvironment in Pancreatic Cancer

Pancreatic cancer (PACA), which is characterized by an immunosuppressive nature, remains one of the deadliest malignancies worldwide. Aberrant DNA methylation (DNAm) reportedly influences tumor immune microenvironment. Here, we evaluated the role of DNA methylation driven genes (MDGs) in PACA throug...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xiao, Mingjia, Liang, Xiangjing, Yan, Zhengming, Chen, Jingyang, Zhu, Yaru, Xie, Yuan, Li, Yang, Li, Xinming, Gao, Qingxiang, Feng, Feiling, Fu, Gongbo, Gao, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866195/ https://www.ncbi.nlm.nih.gov/pubmed/35222383 http://dx.doi.org/10.3389/fimmu.2022.803962

Ejemplares similares

Deciphering the Prognostic Implications of the Components and Signatures in the Immune Microenvironment of Pancreatic Ductal Adenocarcinoma
por: Tang, Rong, et al.
Publicado: (2021)

Identifying a baicalein-related prognostic signature contributes to prognosis prediction and tumor microenvironment of pancreatic cancer
por: Zhang, Citing, et al.
Publicado: (2023)

Evaluating the efficacy and microenvironment changes of HER2 + gastric cancer during HLX02 and Endostar treatment using quantitative MRI
por: Liang, Jianye, et al.
Publicado: (2022)

Development and Verification of the Hypoxia- and Immune-Associated Prognostic Signature for Pancreatic Ductal Adenocarcinoma
por: Chen, Dongjie, et al.
Publicado: (2021)

Comprehensive analysis of pyroptotic gene prognostic signatures associated with tumor immune microenvironment and genomic mutation in breast cancer
por: Zhang, Hongfei, et al.
Publicado: (2022)

Identification of prognostic gene expression signatures based on the tumor microenvironment characterization of gastric cancer
por: Sang, Qingqing, et al.
Publicado: (2022)

Identification and analysis of DNA methylation-driven signatures for prognostic and immune microenvironments evaluation in hepatocellular carcinoma
por: Shen, Bingbing, et al.
Publicado: (2022)

Identification and analysis of necroptosis-associated signatures for prognostic and immune microenvironment evaluation in hepatocellular carcinoma
por: Lu, Juan, et al.
Publicado: (2022)

An integrated overview of the immunosuppression features in the tumor microenvironment of pancreatic cancer
por: Guo, Jinglong, et al.
Publicado: (2023)

An Eight-Gene Hypoxia Signature Predicts Survival in Pancreatic Cancer and Is Associated With an Immunosuppressed Tumor Microenvironment
por: Abou Khouzam, Raefa, et al.
Publicado: (2021)

Comprehensive Analysis of m6A RNA Methylation Regulators and the Immune Microenvironment to Aid Immunotherapy in Pancreatic Cancer
por: Guo, Yongdong, et al.
Publicado: (2021)

m(6)A Methylation Modification Patterns and Tumor Microenvironment Infiltration Characterization in Pancreatic Cancer
por: Sun, Mengyu, et al.
Publicado: (2021)

Regulatory T-cells-related signature for identifying a prognostic subtype of hepatocellular carcinoma with an exhausted tumor microenvironment
por: Zhang, Genhao
Publicado: (2022)

Revealing the role of regulatory T cells in the tumor microenvironment of lung adenocarcinoma: a novel prognostic and immunotherapeutic signature
por: Zhang, Pengpeng, et al.
Publicado: (2023)

Combined signature of N7-methylguanosine regulators with their related genes and the tumor microenvironment: a prognostic and therapeutic biomarker for breast cancer
por: Li, Tingjun, et al.
Publicado: (2023)

LATPS, a novel prognostic signature based on tumor microenvironment of lung adenocarcinoma to better predict survival and immunotherapy response
por: Huang, Jihong, et al.
Publicado: (2022)

Characterization and validation of a ferroptosis-related LncRNA signature as a novel prognostic model for lung adenocarcinoma in tumor microenvironment
por: Wang, Yuanyong, et al.
Publicado: (2022)

Identification of a DNA Methylation-Driven Genes-Based Prognostic Model and Drug Targets in Breast Cancer: In silico Screening of Therapeutic Compounds and in vitro Characterization
por: Tian, Saisai, et al.
Publicado: (2021)

Construction and comprehensive analysis of a novel prognostic signature associated with pyroptosis molecular subtypes in patients with pancreatic adenocarcinoma
por: Huang, Qian, et al.
Publicado: (2023)

Analysis of m6A-Related Signatures in the Tumor Immune Microenvironment and Identification of Clinical Prognostic Regulators in Adrenocortical Carcinoma
por: Jin, Yi, et al.
Publicado: (2021)

Identification of Ferroptosis-Related Prognostic Signature and Subtypes Related to the Immune Microenvironment for Breast Cancer Patients Receiving Neoadjuvant Chemotherapy
por: Xu, Yuhao, et al.
Publicado: (2022)

Pancreatic cancer and fibrosis: Targeting metabolic reprogramming and crosstalk of cancer-associated fibroblasts in the tumor microenvironment
por: Li, Xin, et al.
Publicado: (2023)

From the Immune Profile to the Immunoscore: Signatures for Improving Postsurgical Prognostic Prediction of Pancreatic Neuroendocrine Tumors
por: Wei, Miaoyan, et al.
Publicado: (2021)

Hypoxia-Driven Immunosuppressive Metabolites in the Tumor Microenvironment: New Approaches for Combinational Immunotherapy
por: Li, Yiliang, et al.
Publicado: (2018)

Identification of Prognostic Genes in the Tumor Microenvironment of Hepatocellular Carcinoma
por: Xiang, Shixin, et al.
Publicado: (2021)

Prognostic significance and immune infiltration of microenvironment-related signatures in pancreatic cancer
por: Lu, Qian, et al.
Publicado: (2021)

Interplay of four types of RNA modification writers revealed distinct tumor microenvironment and biological characteristics in pancreatic cancer
por: Gao, Wenzhe, et al.
Publicado: (2022)

Vascular normalization: reshaping the tumor microenvironment and augmenting antitumor immunity for ovarian cancer
por: Yu, Ping, et al.
Publicado: (2023)

Immune Gene Signatures and Immunotypes in Immune Microenvironment Are Associated With Glioma Prognose
por: Wang, Xiang-Xu, et al.
Publicado: (2022)

Type 2 and Type 17 Invariant Natural Killer T Cells Contribute to Local Eosinophilic and Neutrophilic Inflammation and Their Function Is Regulated by Mucosal Microenvironment in Nasal Polyps
por: Ye, Xiaoyan, et al.
Publicado: (2022)

Unveiling the interplay between mutational signatures and tumor microenvironment: a pan-cancer analysis
por: Luo, Li-Zhi, et al.
Publicado: (2023)

Identification of Methylation Immune Subtypes and Establishment of a Prognostic Signature for Gliomas Using Immune-Related Genes
por: Hu, Zhengang, et al.
Publicado: (2021)

m6A-Regulator Expression Signatures Identify a Subset of Follicular Lymphoma Harboring an Exhausted Tumor Microenvironment
por: Zhang, Tingting, et al.
Publicado: (2022)

Myeloid Cell Classification and Therapeutic Opportunities Within the Glioblastoma Tumor Microenvironment in the Single Cell-Omics Era
por: Larkin, Collin J., et al.
Publicado: (2022)

Construction of a Lactate-Related Prognostic Signature for Predicting Prognosis, Tumor Microenvironment, and Immune Response in Kidney Renal Clear Cell Carcinoma
por: Sun, Zhuolun, et al.
Publicado: (2022)

Immunogenic cell death-related risk signature predicts prognosis and characterizes the tumour microenvironment in lower-grade glioma
por: Cai, Jiayang, et al.
Publicado: (2022)

Prognosis and Characterization of Immune Microenvironment in Acute Myeloid Leukemia Through Identification of an Autophagy-Related Signature
por: Fu, Denggang, et al.
Publicado: (2021)

Identification of a necroptosis-related gene signature as a novel prognostic biomarker of cholangiocarcinoma
por: Xu, Lixia, et al.
Publicado: (2023)

A vasculogenic mimicry prognostic signature associated with immune signature in human gastric cancer
por: Wang, Jie, et al.
Publicado: (2022)

IOBR: Multi-Omics Immuno-Oncology Biological Research to Decode Tumor Microenvironment and Signatures
por: Zeng, Dongqiang, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ki4ekorpp5b73u56ka8nha5279